Dear all,
This is to inform you all that recently, we have launched a website,
named 3D-NuS (http://iith.ac.in/3dnus/), to model non-canonical nucleic
acid structures like DNA/RNA duplexes with mis-match base pairs, DNA/RNA
chimeras, triplexes and G-quadruplexes. We have used Xplor-NIH for model
optimization of the generated models. Complete description of the method
used to generate nucleic acid models through 3D-NUS is given in the
following paper.
https://doi.org/10.1016/j.jmb.2017.06.013
3D-NuS: A Web Server for Automated Modeling and Visualization of
Non-Canonical 3-Dimensional Nucleic Acid Structures.
<https://www.ncbi.nlm.nih.gov/pubmed/28652006>
Patro LPP, Kumar A, Kolimi N, *Rathinavelan* T.
J Mol Biol. 2017 Jun 23. pii: S0022-2836(17)30314-5. doi:
10.1016/j.jmb.2017.06.013.
*Ponoop Patro*
Ph.D scholar
C/O Dr. Thenmalarchelvi Rathinavelan
Dept.of Biotechnology, IIT Hyderabad,
502285.
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