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Hello Nah--

> Is there an example/sample python script that performs just a simple SA
> (something like random.inp) ? the nice examples (anneal.py & refine.py)
> provided in the eginputs dir are great, yet, a simple SA script ( load
> structure, generate extended conformation, add basic potentials (just Xplor
> ones - ANGL,BOND,VdW, etc., maybe the knowledge-based ones - RAMA,COLL) do a
> simple SA from 3000k to 50k, will help me a great deal in understanding more.
> 

sorry- this is what we have for now.

> Also, an explanation for the purpose of doing something like in anneal.py
> (from gb1_rdc) for example, why high-temperature TA dynamics, cooling steps
> and low temp minimization in Cartesian coordinates ( role of ramping up some
> params and the corresponding use of helper functions,classes etc.,) - what
> happens if this is not done ? Can one get convergence just with a SA in TA or
> Cartesian space etc., are some other things where the inputs will be
> appreciated. The Xplor manual (with examples only using xplor interface)
> doesn't help much the one who is getting started from the Xplor-Python
> interface. And the python example scripts,as such, though easier to
> understand/emulate introduce many things, which are better understood and
> used rather than just emulated. Some more basic examples will help here.
> 

The protocols have been refined over the (many) years to optimize
convergence and minimize computational effort. Other groups use
different algorithms, and we're very interested if someone comes up with
a better protocol.

I hope this helps--
Charles
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