Al-Mushaf  TIDAK mengharamkan cholesterol

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Researchers learn that some 'good cholesterol' isn't good enough
Published: Monday, December 1, 2008 - 00:56 in Health & Medicine

Learn more about: cholesterol hdl cholesterol ldl faseb journal gerald 
weissmann good cholesterol lipid chemistry

If you think your levels of "good cholesterol" are good enough, a new study 
published in the December 2008 issue of The FASEB Journal suggests that you may 
want to think again. In the report, researchers from the University of Chicago 
challenge the conventional wisdom that simply having high levels of good 
cholesterol (HDL) and low levels of bad cholesterol (LDL) is necessary for good 
heath. Instead, they show that the good cholesterol has varying degrees of 
quality and that poor quality HDL is actually bad for you. "For many years, HDL 
has been viewed as good cholesterol and has generated a false perception that 
the more HDL in the blood, the better," said Angelo Scanu, M.D., a pioneer in 
blood lipid chemistry from University of Chicago and first author of the study. 
"It is now apparent that subjects with high HDL are not necessarily protected 
from heart problems and should ask their doctor to find out whether their HDL 
is good or bad."

The researchers came to this conclusion after reviewing published research on 
this subject. In their review, they found that the HDL from people with chronic 
diseases such as rheumatoid arthritis, kidney disease, and diabetes is 
different from the HDL in healthy individuals, even when blood levels of HDL 
are comparable. They observed that normal, "good," HDL reduces inflammation, 
while the dysfunctional, "bad," HDL does not.

"This is yet one more line of research that explains why some people can have 
perfect cholesterol levels, but still develop cardiovascular disease," said 
Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "Just as the 
discovery of good and bad cholesterol rewrote the book on cholesterol 
management, the realization that some of the 'good cholesterol' is actually bad 
will do the same."
Source: Federation of American Societies for Experimental Biology

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