saya///pamit..untuk sementara saya keluar dulu dari balita...nanti gabung lagi deh....makasih
Pyoderma gangrenosum is a disease that causes tissue to become necrotic,
causing deep ulcers that usually occur on the legs. When they occur, they
can lead to chronic wounds. Ulcers usually initially look like small bug
bites or papules, and they progress to larger ulcers. Though the wounds
rarely lead to death, they can cause pain and scarring.

The disease was identified in 1930. It affects approximately 1 person in
100,000 in the population. Though it can affect people of any age, it mostly
affects people in their 40s and 50s.[1]


[edit] Types

Pyoderma gangrenosum
There are two main types of pyoderma gangrenosum:[1]

  a.. the normal ulcerative form, which occurs in the legs
  b.. an 'atypical' form that is more superficial and occurs in the hands
and other parts of the body
Other variations are[2]:

  a.. Peristomal pyoderma gangrenosum is 15% of all cases of pyoderma
  b.. Bullous pyoderma gangrenosum
  c.. Pustular pyoderma gangrenosum[3]
  d.. Vegetative pyoderma gangrenosum[4]

[edit] Causes
Though the etiology is not well understood, the disease is thought to be due
to immune system dysfunction, and particularly improper functioning of
neutrophils. At least half of all pyoderma gangrenosum patients also suffer
from illnesses that affect their systemic function.[1] For instance, around
2% of Crohn's disease sufferers have the condition.


[edit] Associations
The common conditions associated with pyoderma gangrenosum are:


Inflammatory bowel disease: Chronic ulcerative colitis Crohn's disease

Arthritides:

Rheumatoid arthritis Seronegative symetrical polyarthritis

Haematological disease:

Myelocytic leukaemia Hairy cell leukaemia Myelofibrosis Myeloid metaplasia
Monoclonal gammopathy (IgA) [5]


[edit] Treatment
A number of treatment options exist.[6]


[edit] References
  1.. ^ a b c Jackson JM and Callen JP. 2006. Emedicine: Pyoderma
Gangrenosum. Retrieved on January 23, 2007.
  2.. ^ Brooklyn T, Dunnill G, Probert C (2006). "Diagnosis and treatment of
pyoderma gangrenosum". BMJ 333 (7560): 181-4. doi:10.1136/bmj.333.7560.181.
PMID 16858047.
  3.. ^ Shankar S, Sterling JC, Rytina E (2003). "Pustular pyoderma
gangrenosum". Clin. Exp. Dermatol. 28 (6): 600-3.
doi:10.1046/j.1365-2230.2003.01418.x. PMID 14616824.
  4.. ^ Langan SM, Powell FC (2005). "Vegetative pyoderma gangrenosum: a
report of two new cases and a review of the literature". Int. J. Dermatol.
44 (8): 623-9. doi:10.1111/j.1365-4632.2005.02591.x. PMID 16101860.
  5.. ^
http://www.gpnotebook.com/simplepage.cfm?ID=-771358647&linkID=28508&cook=no
  6.. ^ Reichrath J, Bens G, Bonowitz A, Tilgen W (2005). "Treatment
recommendations for pyoderma gangrenosum: an evidence-based review of the
literature based on more than 350 patients". J. Am. Acad. Dermatol. 53 (2):
273-83. doi:10.1016/j.jaad.2004.10.006. PMID 16021123.

[edit] External links
  a.. DermNet reactions/pyoderma-gangrenosum




----- Original Message -----
From: "fiona" <[EMAIL PROTECTED]>
To: <balita-anda@balita-anda.com>
Sent: Friday, February 15, 2008 10:00 AM
Subject: [balita-anda] Tanya: Pioderma pada bayi baru lahir


Dear Smart Parents,

Ponakanku baru lahir tgl 11 Feb kemarin via caesar karena ibunya placenta
previa (anak ke 2).
Yang mengejutkan, waktu mau pulang kemarin, si baby gag boleh pulang dulu,
harus dirawat intensif karena kata dokter dia kena Pioderma, sejenis
penyakit kulit.
Tp yang membingungkan ibunya, waktu baru lahir dia gak dibilangin ttg hal
ini, ternyata di bagian punggung agak keatas si baby, ada spt luka segede
jempol org dewasa & bernanah.
Oleh dokter yg merawat dibilangin sdh dikasih obat dan luka sudah mulai
mengering....
Baby-nya sih gak rewel, mungkin belum yah... tp menurut info dr dokter,
penyakit ini adalah bakteri yang bisa menular.. dan tidak boleh
digabungkan
dengan bayi lain krn takut menular.

Ada yang tahukah ttg penyakit Pioderma/Fioderma ini ? aku sdh coba
googling,
tp kurang jelas krn adanya bahasa asing (bukan inggris), yg dr web
indonesia
kurang informatif.

Thanks yah, karena ibunya msh lemas abis operasi dan bapaknya lagi kerja
di
Amrik... any info akan sangat membantu.. oiya, si baby tidak dirawat di
Jakarta, tp di Bogor....

Terima kasih atas perhatiannya,
fiona




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