TGen Researcher Honored by Science Spectrum Magazine 

Dr. John Carpten named a top minority in science 

10-03-2006

October 3, Phoenix, AZ--Dr. John Carpten, senior investigator and 
director of the Integrated Cancer Genomics Division at the 
Translational Genomics Research Institute (TGen), has been named 
a "Trailblazer" by Science Spectrum magazine. The Trailblazers are 
outstanding Hispanic, Asian American, Native American, and Black 
professionals in the science arena whose leadership and innovative 
thinking on the job and in the community extend throughout and 
beyond their industry. 
Selected by the magazine's editors, the chosen winners have all made 
a significant, quantifiable, personal impact on the industry and 
their communities. Many maintain a powerful position of influence 
regarding public policy for minorities in science. 


 
Dr. John Carpten, senior investigator and director of TGen's 
Integrated Cancer Genomics Division was recently named 
a "Trailblazer" by Science Spectrum magazine. The trailblazer award 
is presented to Black, Hispanic, Asian American, and Native American 
professionals in the science arena whose leadership and innovative 
thinking on the job and in the community extend throughout and 
beyond their industry. 

"There is an immediacy associated with helping patients with cancer 
and it is this immediacy that drives my research forward," said Dr. 
Carpten. "It is a such an honor to be recognized by Science Spectrum 
magazine and I hope to set an example for other minorities in the 
field of science." 

Dr. Carpten's work at TGen is focused on searching for genetic 
identifiers that will act as predictors for prostate cancer, a 
disease whose incidence is three times more likely in African 
American men and six times more likely to lead to death in that 
population. He is currently leading the effort to conduct the most 
in-depth study of its kind designed to scan the genomes of families 
with prostate cancer to identify genetic risk factors for the 
disease. Once these risk factors are identified, scientists can use 
that information to develop diagnostic and prognostic tools to help 
physicians treat their patients. His research in this area is 
supported by the National Cancer Institute at the National 
Institutes of Health. 

In addition to prostate cancer, Dr. Carpten is also working on adult 
hematological malignancies, particularly multiple myeloma, a disease 
that again disproportionately affects African Americans. In 
collaboration with Mayo Clinic Scottsdale and Agilent Technologies, 
Dr. Carpten's studies are focused on identifying important 
biomarkers associated with multiple myeloma development. 

He is also the laboratory project leader for the Multiple Myeloma 
Genomic Initiative, a multi-million dollar research program designed 
to rapidly accelerate progress made against multiple myeloma by 
significantly improving the understanding of the biology of the 
disease. This initiative is the most comprehensive research 
collaboration of its kind that focuses on cancer genomics. This work 
is funded through the Multiple Myeloma Research Consortium. 

"Dr. Carpten is an exceptionally talented cancer investigator with 
an unparalleled compassion for patients and dedication to finding 
answers," said Dr. Jeffrey Trent, TGen's Scientific Director. "His 
work stands at the forefront of bringing laboratory results into 
clinical benefit." 

# # # 

About TGen
The Translational Genomics Research Institute (TGen) is a non-profit 
501(c)(3) organization focused on developing earlier diagnostics and 
smarter treatments. Translational genomics research is a relatively 
new field employing innovative advances arising from the Human 
Genome Project and applying them to the development of diagnostics, 
prognostics and therapies for cancer, neurological disorders, 
diabetes and other complex diseases. TGen's research is based on 
personalized medicine. The institute plans to accomplish its goals 
through robust and disease-focused research. 

 
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