Hi folks:
A colleague has an antibody they would like a crystal structure of,
bound to a peptide. Currently it is a whole antibody. From my
superficial search of the literature, it looks like everyone uses Fab
fragments in such cases. Is this true, and is it stupid to try the
whole thing? If anyone would be kind enough to point me to a good
methodological overview for crystallizing these things in the
literature, I would be exceptionally grateful.
Many thanks.
Bill
William G. Scott
Contact info:
http://chemistry.ucsc.edu/~wgscott/
