Hello All, I'm delighted to announce that Dr. Bernhard Rupp will give a scientific presentation in Rigaku Crystallization Webinar on August 6, 2013, 8:00am Pacific Standard Time. The webinar is free to attend and all are welcome. You can register it through our web page, http://www.rigakuautomation.com/webinars. Here is the detail of the presentation:
"Nature, properties and genesis of protein crystals Presenter: Dr. Bernhard Rupp, k.k Hofkristallamt, USA/Innsbruck Medical University, Austria Date and time: Thursday, August 6th, 2013, 8:00am Pacific Standard Time Protein crystallization is the self-assembly of protein molecules into an ordered, periodic structure, the protein crystal. Protein molecules however are large, complex, and flexible macromolecules and most proteins are therefore difficult to crystallize. To understand how to find conditions that allow crystal formation, we must first understand the physico-chemical nature of proteins and how to modify their solubility and local surface property distribution. Once we understand what conditions must be fulfilled for crystallization to occur, the question is how to efficiently sample the magnitude of possible reagent combinations that might provide the right conditions. The initial screening or sampling then informs us how to proceed further and how to optimize crystal growth, and often also indicates that further examination and in most cases, modification of the protein itself may be necessary to achieve successful crystallization." Thank you, Jian Xu, Ph.D. Rigaku Automation, Inc. www.rigakuautomation.com
