H3 Biomedicine seeks to recruit an outstanding postdoctoral candidate in structural biology. Our major area of research is RNA splicing in cancer. We have developed tool molecules targeting aberrant splicing in SF3B1 mutant cancers. Our goal is to understand the structural basis for aberrant splicing in this mutant background and use the tool molecules as a platform for structure based drug design.
Relevant Review: http://www.nature.com/nrd/journal/v11/n11/full/nrd3823.html Qualifications The applicant must have a Ph.D. with a strong background in recombinant protein expression, crystallization, and structure determination. Experience in biophysics is also desirable. Candidate should be highly motivated and results driven. Strong organizational and interpersonal skills are desired. Funding is for three years with competitive salary and benefits. The laboratory is newly equipped. The candidate will be integrated into a dynamic and collaborative work environment with: * Regular interactions with mentor and potential for external academic advisor as appropriate * Regular presentations at Scientific Founders Meeting to the H3 Biomedicine senior scientists and our academic founders Stuart Schreiber, PhD and Todd Golub, MD. * Presentation/publication of research at major scientific conferences/journals * Potential for transition into full-time employment should appropriate positions be available at the end of the postdoctoral position To apply for this position, submit your resume at: http://www.h3biomedicine.com/career/postdoctoral-fellows-oncology-research Or e-mail: nicholas_lar...@h3biomedicine.com -- [This e-mail message may contain privileged, confidential and/or proprietary information of H3 Biomedicine. If you believe that it has been sent to you in error, please contact the sender immediately and delete the message including any attachments, without copying, using, or distributing any of the information contained therein. This e-mail message should not be interpreted to include a digital or electronic signature that can be used to authenticate an agreement, contract or other legal document, nor to reflect an intention to be bound to any legally-binding agreement or contract.]
