Picking up the mail of Pavel, Phenix refines occupancies..
If you expect the loops to be disordered, did you try to lower the
occupancy of these residues, following Ethan Merritt statement that
"general uncertainty [...] is represented better by occupancy <1
rather than an arbitrary large B factor"
(To B or not to B, doi:10.1107/S0907444911028320).
If this attempt does not bring the
B-factors down, it will surely make the model more accurate, as the atom
coordinates of the loops may not be correct at all, no?
matthias
>>> Pavel Afonine <pafon...@gmail.com> 14.10.16 9.36 Uhr >>>
If you are still worry about your Bfactor, you could try
TLS,
Or NCS, but SA with MLHL might be better.
(A joke).
