-Caveat Lector-

Science 13 July 2007: Vol. 317. no. 5835, pp. 215 - 219 DOI:  
10.1126/science.1139560 Research Articles - Prefrontal Regions Orchestrate  
Suppression of 
Emotional Memories via a Two-Phase Process - Brendan E. Depue,  Tim Curran, 
Marie T. Banich Whether memories can be suppressed has been a  controversial 
issue 
in psychology and cognitive neuroscience for decades. We  found evidence that 
emotional memories are suppressed via two  time-differentiated neural 
mechanisms: (i) an initial suppression by the right  inferior frontal gyrus 
over 
regions supporting sensory components of the memory  representation (visual 
cortex, thalamus), followed by (ii) right medial frontal  gyrus control over 
regions 
supporting multimodal and emotional components of the  memory representation 
(hippocampus, amygdala), both of which are influenced by  fronto-polar 
regions. These results indicate that memory suppression does occur  and, at 
least in 
nonpsychiatric populations, is under the control of prefrontal  
regions.....E-mail: depue{at}colorado.edu 
_http://www.sciencemag.org/cgi/content/abstract/317/5835/215_ 
(http://www.sciencemag.org/cgi/content/abstract/317/5835/215) 



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