In a message dated 5/9/00 3:01:05 PM Central Daylight Time, AOL News writes:

<< Subj:    Tests Urged for Drug-Resistant HIV
 Date:  5/9/00 3:01:05 PM Central Daylight Time
 From:  AOL News
 BCC:   Ahab42

 Tests Urged for Drug-Resistant HIV

 .c The Associated Press

  By LINDSEY TANNER

 CHICAGO (AP) - Tests that help identify drug-resistant strains of the AIDS
virus should be routinely used in most infected patients to help doctors
customize their treatment, an advisory panel says.

 Patients with drug-resistant strains are at greater risk of developing
full-blown AIDS.

 Because the AIDS virus tends to mutate rapidly, becoming resistant to drugs,
patients generally receive a combination of medicines. But initial treatment
fails in about half of all AIDS patients, and doctors frequently have to
change the treatment to keep up with mutations.

 In Wednesday's Journal of the American Medical Association, a panel of the
International AIDS Society-USA said doctors should consider routine testing
for virtually all HIV-infected patients except those whose infection is
already being successfully treated.

 Two types of tests help determine resistance: Genotype tests identify
genetic mutations known to be resistant. And phenotype tests determine
whether a drug will kill a patient's virus strain.

 Both tests are costly, running about $400 to $1,000 each, Dr. Charles
Flexner of the Johns Hopkins University School of Medicine said in an
accompanying editorial. Also, it can take up to a month to get results, and
the tests are not foolproof and may produce false-negative results, he said.

 The International AIDS Society-USA is a nonprofit program for doctors
involved in HIV and AIDS care. It works to improve AIDS treatment.

 AP-NY-05-09-00 1600EDT

  Copyright 2000 The Associated Press.  The information  contained in the AP
news report may not be published,  broadcast, rewritten or otherwise
distributed without  prior written authority of The Associated Press.



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Tests Urged for Drug-Resistant HIV

.c The Associated Press

 By LINDSEY TANNER

CHICAGO (AP) - Tests that help identify drug-resistant strains of the AIDS virus 
should be routinely used in most infected patients to help doctors customize their 
treatment, an advisory panel says.

Patients with drug-resistant strains are at greater risk of developing full-blown AIDS.

Because the AIDS virus tends to mutate rapidly, becoming resistant to drugs, patients 
generally receive a combination of medicines. But initial treatment fails in about 
half of all AIDS patients, and doctors frequently have to change the treatment to keep 
up with mutations.

In Wednesday's Journal of the American Medical Association, a panel of the 
International AIDS Society-USA said doctors should consider routine testing for 
virtually all HIV-infected patients except those whose infection is already being 
successfully treated.

Two types of tests help determine resistance: Genotype tests identify genetic 
mutations known to be resistant. And phenotype tests determine whether a drug will 
kill a patient's virus strain.

Both tests are costly, running about $400 to $1,000 each, Dr. Charles Flexner of the 
Johns Hopkins University School of Medicine said in an accompanying editorial. Also, 
it can take up to a month to get results, and the tests are not foolproof and may 
produce false-negative results, he said.

The International AIDS Society-USA is a nonprofit program for doctors involved in HIV 
and AIDS care. It works to improve AIDS treatment.

AP-NY-05-09-00 1600EDT

 Copyright 2000 The Associated Press.  The information  contained in the AP news 
report may not be published,  broadcast, rewritten or otherwise distributed without  
prior written authority of The Associated Press.



Announcement: America Online has added Reuters newswires to News Profiles. To add 
Reuters articles to your daily news delivery, go to KW: <A HREF="aol://5862:146">News 
Profiles</A> and click on "Modify Your News Profiles." Then click "Edit" and add 
Reuters from the list on the left.

To edit your profile, go to keyword <A HREF="aol://1722:NewsProfiles">NewsProfiles</A>.
For all of today's news, go to keyword <A HREF="aol://1722:News">News</A>.


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