It is well established that there are species specific biases in codon and dicodon usage which strongly affect the efficiency of mRNAs translation. There are a few companies offering protein production services, based on calculating these biases and "recoding" mRNAs for better expression in new host species.
I have worked up dicodon calculation software, which I want to put in the public domain. The problem is that I have no formal IT training the code is a heterogenous hack. It draws on: some EMBOSS binaries PERL scripts donated by my son (an IT professional) and some Linux binaries all called through my hack of a master BASH script It would clearly be best of all of the above could be combined into some EMBOSS functionality. Thus a collaborator(s) are being sought to wok this through. I am 72 and retired, and do not at this time want to start a new career learning C coding. So anyone interested please contact me. Through mid March I am traveling until returning to the Wash DC area. So my responses may be slow until then. Sincerely: Marvin Stodolsky, Ph.D Biophysics retired from the US Dept. of Energy, Office of Science, Office of Biological & Environ. Rsch _______________________________________________ EMBOSS mailing list EMBOSS@lists.open-bio.org http://lists.open-bio.org/mailman/listinfo/emboss