Exchange 2016 CU5, Exchange 2013 CU16, Exchange 2010 SP3 UR17, and Exchange 
2007 SP3 UR23 all release today.

This is the very last release for Exchange 2007.

Exchange 2016 CU5 fixes several problems that I have personally seen with my 
customers. I recommend you install it.

Exchange 2016 CU5 and Exchange 2013 CU16 require .NET 4.6.2. If you are 
upgrading from anything older than Exchange 2016 CU4 (or Exchange 2013 CU15), 
you are recommended to do a two-phase upgrade.

https://blogs.technet.microsoft.com/exchange/

At this writing, the blog post isn't yet available everywhere. It should be 
within a couple of hours.

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