Thanks Amani.  I agree with you.  

Shelley 


> On Oct 18, 2018, at 6:34 PM, Amani Oakley <aoak...@oakleylegal.com> wrote:
> 
> Hi Shelley. Thanks for clarifying. I really didn’t know that prednisolone 
> could have negative effects on the heart. However, I have had the experience 
> of a cat with a heart murmur. Eventually, after we had looked after her for a 
> while, the heart murmur disappeared.
>  
> However, if your cat pants after playing for a while, you are right that one 
> of the reasons may well be heart issues.
>  
> You obviously have a terrific heart to take in a feral like that and keep him 
> when you found he was positive. What a nice person.
>  
> Thanks for the info. Unfortunately, though, again, I kinda feel that in some 
> circumstances like FeLV, whether there are potential side-effects from some 
> of the meds, there are few choices and I would probably take the risk if my 
> cat was doing poorly (as mine was). Thank you though for that information, 
> which I definitely did not know. I will have to keep it in mind.
>  
> Amani
>  
> From: Felvtalk <felvtalk-boun...@felineleukemia.org> On Behalf Of Shelley 
> Theye
> Sent: October 18, 2018 6:27 PM
> To: felvtalk@felineleukemia.org
> Subject: Re: [Felvtalk] Batman Felv Positive Having Neurological issues.
>  
> Hi Amani,
>  
> I was speaking about corticosteroids- Prednisone or Prednisolone.  Sorry for 
> any confusion.
> I have a cat, Jack, with heart disease who also has IBD so he cannot have 
> steroids.
> I believe there is one, which is called Budesonide?  that might act more 
> locally in the intestines so 
> it could be a bit safer if a cat has heart disease.  
>  
> My FeLV positive cat Leo, who became sick quickly back in 2014, was diagnosed 
> with both Lymphoma and 
> leukemia, his WBC count was through the roof, in the 150,000’s??  I would 
> have to go back and look at the notes.
> He was @ 5 years old. I trapped him in a neighbor’s yard to TNR, but 
> he tested positive so I kept him. Anyway, after the vet visit, for mainly 
> inappetence, he went downhill
> very quickly and I thought the stress of the visit, x-rays, fluids, and pred. 
> might have sent him into heart failure too.
> That was a guess on my part.  He was an adult feral that I tamed once he 
> tested positive for FeLV, and he was so afraid 
> out of his environment that I never took him to get an echo.  I only 
> suspected it as a possibility because he 
> had a murmur when he was neutered, though not later, and would pant when 
> playing too much with feather toy.
> Something I will never know and it has always eaten away at me.
>  
> I am not in this group much anymore, but read the messages, and just wanted 
> to mention to Katy, just in case.
> Hopefully not that.
>  
> Shelley 
>  
>  
>  
>  
>  
>  
> 
> 
> 
> On Oct 18, 2018, at 4:59 PM, Amani Oakley <aoak...@oakleylegal.com 
> <mailto:aoak...@oakleylegal.com>> wrote:
>  
> Sorry Shelley – my email below should have read IT ISN”T prednisolone. . . 
>  
> Amani
>  
> From: Felvtalk <felvtalk-boun...@felineleukemia.org 
> <mailto:felvtalk-boun...@felineleukemia.org>> On Behalf Of Amani Oakley
> Sent: October 18, 2018 4:57 PM
> To: felvtalk@felineleukemia.org <mailto:felvtalk@felineleukemia.org>
> Subject: Re: [Felvtalk] Batman Felv Positive Having Neurological issues.
>  
> Hi Shelley. Are you speaking about anabolic steroids or corticosteroids? And 
> what type in particular? I think that there may be a particular steroid which 
> has been linked with heart issues sometimes but it is prednisolone (which is 
> a corticosteroid) and it isn’t Winstrol (which is an anabolic steroid).
>  
> Amani
>  
> From: Felvtalk <felvtalk-boun...@felineleukemia.org 
> <mailto:felvtalk-boun...@felineleukemia.org>> On Behalf Of Shelley Theye
> Sent: October 18, 2018 4:29 PM
> To: felvtalk@felineleukemia.org <mailto:felvtalk@felineleukemia.org>
> Subject: Re: [Felvtalk] Batman Felv Positive Having Neurological issues.
>  
> Hi Katy,
>  
> So sorry that Batman is going through this!
>  
> Did they look at Batman’s heart while he was at the vet hospital?  
> Specifically did they do an echocardiogram?  I am guessing that they had no 
> reason to with his initial symptoms so they probably didn’t?
>  
> Maybe he has heart disease that the steroids have exacerbated... Young cats 
> can have it and not have any outward symptoms.  Steroids are contraindicated 
> with heart problems.  I think there is one type that can be used, but it is 
> not usually given first.  
>  
> Just throwing this out there just in case.  Steroids could hurt his heart if 
> he has undiagnosed heart problem and maybe cause him to act like.
> Not to scare you, just to get him treated for it if it is that.
>  
> Shelley   
>  
>  
>  
> 
> On Oct 18, 2018, at 3:27 PM, Katy Brown <ktbrow...@gmail.com 
> <mailto:ktbrow...@gmail.com>> wrote:
>  
> Amani,
> That is very insightful. I’m not convinced he has lymphoma because his 
> decline was so rapid. Within hours he went from walking to having completely 
> rigid legs. And today he is starting to decline. I’m wondering if there is 
> something else I can give him besides the 5 mg of Prednisolone and the 
> Clindamycin.
> The vet said he he keeps declining we could do another form of Chemo which is 
> very aggressive and has other side affects and would be a Hail Mary to buy 
> him another few days? 
> I’m just not convinced he has cancer. Even though he is FeLV positive he is 
> young to develop a cancer? 
> Sent from my iPhone
> 
> On Oct 18, 2018, at 12:54 PM, Amani Oakley <aoak...@oakleylegal.com 
> <mailto:aoakley@oakleylegalcom>> wrote:
> 
> I actually had a few similar experiences. Once it involved two very young 
> kittens. Once it involved a cat about a year old. In my opinion, the two 
> different experiences had two different causative agents, and at the risk of 
> boring you silly, I will try to explain both. Neither, by the way, was well 
> understood by the vets, leading me again to the inevitable conclusion that 
> cat health is very poorly studied (no where near dog health) and because cats 
> respond different to disease and medication, (whereas dogs respond very much 
> like people), then science and medicine is way behind in understanding cats.
>  
> With respect to the kittens, it was my view that they actually had (and one 
> of them still has) Lyme disease. The area I picked them up was one very 
> well-known to be endemic for Lyme disease. They had an alternating lameness – 
> once picking up one paw which seemed very swollen and sore – and then next 
> day, picking up the other paw. I looked this up and saw that this alternating 
> lameness was described in dogs with Lyme disease. However, my vet believed 
> that it might be calici virus. I didn’t agree with her, but let her treat for 
> calici virus (including vaccination). The acute phase of the response seemed 
> to be limited in time, and both kittens seemed to get better on their own. 
> However, their brother lapsed into a coma – was literally unresponsive for 
> hours while I sat up with him. I didn’t know what to do, and my view was that 
> either there was inflammation of the meninges (sac surrounding the brain) or 
> an inflammation of the brain itself, causing increased intracranial pressure 
> which might also result in loss of consciousness. I superdosed him with 
> transdermal prednisone, took him to bed with me and kept checking him for 
> hours. Then, suddenly, at about 4 in the morning, he just bounded awake, and 
> began playing and galavanting all over the bed. Meanwhile, though, one of his 
> two sisters has never been the same. She lost HUGE amounts of weight, and 
> even now, as a 2+ year old cat, she weighs less than many kittens and she is 
> all bones. I have been treating her with a combination of Winstrol, 
> Doxycycline, high prednisone doses and magnesium (her muscles don’t work 
> right – like they are constantly spastic, and she walks in a funny tip toe 
> way, and has poor coordination jumping on things and going up stairs, etc.) 
> Anyhow, she is starting to get better, starting to put on weight and starting 
> to walk better. I am convinced this was and is Lyme disease, though 
> scientists and vets say that cats don’t get it. I don’t know how they know 
> this, because they DO NOT TEST cats for it.
>  
> Story number two involves a kitten I got who was described as a “wobbly” 
> kitten and it was assumed that his mom had suffered a viral infection when he 
> was in utero, which can result in this type of neurological damage (and it 
> can be much worse). However, when he was very little, he suddenly and without 
> warning, decided to squat and pee right in the middle of our bed, and he had 
> never done this before. He was looking straight at me and I felt that he 
> didn’t know why he was doing what he was doing. Not too long after (a few 
> weeks or maybe a month), he started showing some very alarming neurological 
> symptoms, including a loss of muscle control in the back end. His rectum 
> seemed not tight but loose and stool just “fell out” rather than being pushed 
> out. His back legs in particular also became very very weak, and he developed 
> a “tripod stance” – both back legs together – his back end would sway and he 
> would fall down. My knowledge with humans is that this occurs when there is 
> damage to nerves in the spinal column, or pressure on them from a herniated 
> disc, or something like that (cauda equina syndrome). I took him to the 
> emergency clinic, but I had already started him on Winstrol and Prednisolone, 
> assuming that the Prednisolone would help with reduction of swelling in the 
> spinal canal and thus take pressure off the affected nerves, and the Winstrol 
> might help in healing whatever injury there was in the spinal column. By the 
> time they could do an MRI on him, he was regaining all function and his gait 
> had become normal. The MRI was inconclusive, with the vets thinking that they 
> could possible see the remains of a lesion, right in the area where one would 
> expect it to be to affect rectal control and muscle function of the back 
> legs, but the lesion appeared to be healed over so they couldn’t tell if that 
> was the cause or if the lesion was old or new.  
>  
> It sounds to me like the prednisone you used in your case, has a similar 
> effect. There was swelling somewhere, likely in the spinal column as you 
> surmise, and the prednisone helped bring down the swelling.
>  
> Amani
>  
> From: Felvtalk <felvtalk-boun...@felineleukemia.org 
> <mailto:felvtalk-boun...@felineleukemia.org>> On Behalf Of katy brown
> Sent: October 18, 2018 12:21 PM
> To: Felvtalk@felineleukemia.org <mailto:Felvtalk@felineleukemia.org>
> Subject: [Felvtalk] Batman Felv Positive Having Neurological issues.
>  
> Hello,
> I have an amazing cat named Batman who a year ago as a kitten tested positive 
> for FelV. His brother also texted positive, after 2 other tests later on 
> after the antibodies from the mother had cleared, Batman still tested 
> positive while his brother was negative.
>  
> Fast forward a year and both of them were doing great I was away on vacation 
> and left them with a full time cat sitter, who notice about a week ago that 
> Batman was not going up stairs as much, but we figured this could be to him 
> just adjusting to a new person in his home. When I arrived back home I 
> immediately noticed he was not moving well and as the day progressed he was 
> losing more mobility in his front paws. I took him to the emergency room 
> where they thought he had experienced a trauma, and discharged him with 2 
> types of pain meds. The pain meds were a disaster, and he lost further 
> mobility. From there we took him to Pennsylvania Vet. Hospital, which is 
> supposed to be one of the best in the country, they realized he was having 
> neurological issues, did a bunch of testing, his vitals and blood work were 
> all good. An x-ray revealed no masses in his chest or spine. At this point 
> they felt it was a cancer in his column, most likely lymphoma. The Vet 
> thought that he was quite young even given his FeLV positive status to have 
> lymphoma, but given how fast he was becoming completely paralyzed, there were 
> not many other diagnosis that fit the bill. The vet started him on 
> Prednisolone and Clindamycin, and within hours he regained movement in his 
> legs and was walking again. Yesterday he was jumping and scratching on his 
> post again, and eating and drinking. Last night his behavior changed and he 
> kept trying to hide which is very unlike him, however I thought that maybe he 
> was just tired, he had gone from completely paralyzed to jumping in 3 days. 
> But this morning it was apparent that he was not ok, he did eat after much 
> encouragement, but has moved very very little. I have called the Vet and am 
> waiting to hear back but I'm not optimistic. Has anyone had this experience? 
> I don't want to put him down if there is a chance he could come back but he 
> is hardly moving and seems like him trying to hide was him trying to find a 
> place to pass away quietly. Batman is so young and he is the sweetest cat I 
> have ever owned, and his brother can't get along with out him.  I will try 
> anything to keep him alive but I want him to have a good quality life. Any 
> suggestions would be appreciated.
>  
> Also I apologize if I did not use this forum correctly. I wasn't sure if I 
> emailed the group or how it works so I hope this does work.
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