You can't use qdec for this, you will have to use mris_preproc, mri_surf2surf, mri_glmfit, and mri_glmfit-sim. The first step is the tricky one in that you will have to run mris_preproc twice then merge the two data sets.
For the subjects that you want the left hemisphere, run mris_preproc as "normal" mris_preproc --hemi lh --meas thickness --surfreg fsaverage_sym.sphere.reg --s subject1 --s subject2 --o subjects.lh.sm00.mgh For the right hemi subjects run mris_preproc --hemi lh --meas thickness --surfreg fsaverage_sym.sphere.reg --s subject3/xhemi --s subject4/xhemi --o subjects.rh.sm00.mgh Note above that you still specify --hemi lh but that the subject name changes to subject/xhemi Now concatenate the two files together mri_concat subjects.lh.sm00.mgh subjects.rh.sm00.mgh --o subjects.sm00.mgh Then proceed with smoothing, etc. When you do the glm, make sure that your FSGD file has the proper order of subjects (above it would be subject1, subject2, 3, 4) doug On 04/29/2014 12:07 PM, Paola Valsasina wrote: > Dear Doug, > > I registered with surfreg the hemispheres I would like to analyze. How > should I proceed now for the final statistical vertex-wise analysis? > Should I smooth the surfaces and perform between-group comparison with qdec? > Thank you in advance > Paola > > Paola Valsasina, MSc > Research Fellow > Neuroimaging Research Unit (Director Prof. M. Filippi) > Institute of Experimental Neurology, Division of Neuroscience, > Scientific Institute and University "Vita-Salute" San Raffaele > Via Olgettina 60, 20132 Milan, Italy > -------------------------------------------------------------------------- > IL MIO 5XMILLE VA AL SAN RAFFAELE DI MILANO > PERCHE' QUI LA RICERCA DIVENTA CURA. > CF 07636600962 > SE NON QUI, DOVE? > Info: 5xmi...@hsr.it - http://www.5xmille.org/ > > > Disclaimer added by CodeTwo Exchange Rules 2007 > http://www.codetwo.com > > -----Messaggio originale----- > Da: Douglas N Greve [mailto:gr...@nmr.mgh.harvard.edu] > Inviato: martedì 22 aprile 2014 18.20 > A: Valsasina Paola; Freesurfer@nmr.mgh.harvard.edu > Oggetto: Re: R: R: [Freesurfer] Filipping issue > > > You can register just the hemisphere you want to fsaverage_sym. But if > you have a subject whose right hemi you want, you would run the surfreg > with --rh, but later you would specify that you want the lh of subject/xhemi > > doug > > On 04/22/2014 12:04 PM, Paola Valsasina wrote: >> Sorry, I didn't note I was replying to you only.. >> Anyway, thank you for the reply! So I will apply the command I mentioned > to >> you in my previous e-mail to create flipped RH and LH surfaces for the >> subjects with the right hemisphere affected. >> Should I register to the fsaverage_sym atlas also the subjects I don't > want >> to flip (i.e., those with the left hemisphere affected), to pool them >> together in the statistic with the flipped subjects? >> Thank you again >> Paola >> >> Paola Valsasina, MSc >> Research Fellow >> Neuroimaging Research Unit (Director Prof. M. Filippi) >> Institute of Experimental Neurology, Division of Neuroscience, >> Scientific Institute and University "Vita-Salute" San Raffaele >> Via Olgettina 60, 20132 Milan, Italy >> >> -------------------------------------------------------------------------- >> IL MIO 5XMILLE VA AL SAN RAFFAELE DI MILANO >> PERCHE' QUI LA RICERCA DIVENTA CURA. >> CF 07636600962 >> SE NON QUI, DOVE? >> Info: 5xmi...@hsr.it - http://www.5xmille.org/ >> >> >> Disclaimer added by CodeTwo Exchange Rules 2007 >> http://www.codetwo.com >> >> -----Messaggio originale----- >> Da: Douglas N Greve [mailto:gr...@nmr.mgh.harvard.edu] >> Inviato: martedì 22 aprile 2014 17.56 >> A: Valsasina Paola; Freesurfer@nmr.mgh.harvard.edu >> Oggetto: Re: R: [Freesurfer] Filipping issue >> >> >> Hi Paola, please remember to post to the list and not to us personally. >> thanks! I would still use the xhemi tools for this. If you have N >> subjects, you will get 2*N surfaces aligned to the fsaverage_sym atlas. >> You can then just pick the ones you want to analyze further >> doug >> >> On 04/22/2014 08:34 AM, Paola Valsasina wrote: >>> Dear Doug, >>> >>> We have followed your suggestion and we performed the recon-all analysis >> for >>> all study subjects (till autorecon3) on non-flipped images. >>> >>> I am now reading the instructions on the wiki about the xhemi tool, but I >> am >>> not 100% sure they apply to our case. >>> >>> The wiki instructions describe a comparison between LH and RH within >>> subjects (i.e., an analysis of cortical asymmetry), whereas we would like >>> simply to L-R flip the final surfaces of patients having a RH damage, so >>> that all patients have the damage in the LH. >>> Then, we would like to compare them with control subjects. >>> >>> For this purpose, is it sufficient to register the patients lesioned in >> the >>> RH to the symmetric template with the --xhemi option? >>> >>> (i.e. surfreg --s subject_name --t fsaverage_sym --xhemi --rh --lh) >>> >>> Then, how do we perform final statistical analysis? >>> >>> Thank you in advance for any suggestion! >>> Kind regards >>> Paola >>> >>> >>> >>> Paola Valsasina, MSc >>> Research Fellow >>> Neuroimaging Research Unit (Director Prof. M. Filippi) >>> Institute of Experimental Neurology, Division of Neuroscience, >>> Scientific Institute and University "Vita-Salute" San Raffaele >>> Via Olgettina 60, 20132 Milan, Italy >>> >>> > -------------------------------------------------------------------------- >>> IL MIO 5XMILLE VA AL SAN RAFFAELE DI MILANO >>> PERCHE' QUI LA RICERCA DIVENTA CURA. >>> CF 07636600962 >>> SE NON QUI, DOVE? >>> Info: 5xmi...@hsr.it - http://www.5xmille.org/ >>> >>> >>> Disclaimer added by CodeTwo Exchange Rules 2007 >>> http://www.codetwo.com >>> >>> -----Messaggio originale----- >>> Da: freesurfer-boun...@nmr.mgh.harvard.edu >>> [mailto:freesurfer-boun...@nmr.mgh.harvard.edu] Per conto di Douglas N >> Greve >>> Inviato: giovedì 13 febbraio 2014 21.50 >>> A: freesurfer@nmr.mgh.harvard.edu >>> Oggetto: Re: [Freesurfer] Filipping issue >>> >>> >>> Definitely #2. You should use the xhemi tools >>> http://surfer.nmr.mgh.harvard.edu/fswiki/Xhemi >>> First run them through recon-all as normal, then follow the steps on the >>> wiki. Contact the list again to get instructions for the final analysis. >>> >>> doug >>> >>> >>> On 02/13/2014 08:23 AM, Paola Valsasina wrote: >>>> Dear List, >>>> >>>> we are starting the analysis of cortical thickness for a group of >>>> patients who have only one side affected. The majority of patients >>>> have the left hemisphere affected, but some patients have the right >>>> hemisphere affected. In order to do a group analysis, we would like to >>>> flip the images of some patients, so that the affected side is left >>>> for all subjects. >>>> >>>> Which is the best way to do this: >>>> >>>> 1)flip the 001.mgz volume and perform the entire recon-all pipeline >>>> with flipped images; >>>> >>>> or >>>> >>>> 2)perform the recon-all pipeline with the non-flipped volumes and flip >>>> only the final surfaces for statistical purposes? >>>> >>>> Thank you for any suggestion >>>> >>>> Kind regards >>>> >>>> Paola >>>> >>>> >>>> >>>> _______________________________________________ >>>> Freesurfer mailing list >>>> Freesurfer@nmr.mgh.harvard.edu >>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
