The statistics will work properly, but they do assume that the variances 
are the same in different groups. This assumption is generally ok if you 
have a balanced design, which you don't. Also, your p-values are going 
to be driven by the lowest number of subjects. With only 5 you might not 
see much of an effect


On 07/30/2015 01:53 PM, Dibashree Tamuli wrote:
> Dear Freesufer Experts,
> I would like to ask about any tool of freesurfer for comparing 
> cortical thickness of different sample size. Let me describe: I  have 
> 3 groups of different sample size (n=25, n=15, n=5) and control (n=8). 
> Is it possible to compare ?
>
> Thanks and regards
> Dibashree
> AIIMS, New Delhi
>
>
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