Hello Rob,
Yes, this is what the developer suggested. Normalize each independently, 
then compare between groups.
Thank you,
Jennifer Jackson

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> Dear Jennifer,
>
> Thank you for replying. Please, see below if I correctly understood 
> your suggestions.
>
> We should go for all phastCons conserved elements.
> In order to convert between scales (vertebrates vs placental mammals 
> vs primate-specific), we should first pull down all lod scores from 
> vertebrate, mammalian-specific and primate-specific phastCons 
> elements. Then, in each file, add-up values of lod scores and divide 
> these sums by the number of elements. In this way, we will have three 
> means of lod scores. Do you think this would be the bext way to go about?
> Thank you.
>
> I look forward to receiving your reply.
>
> With best regards,
> /Rob
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> Genome maillist  -  Genome@soe.ucsc.edu
> http://www.soe.ucsc.edu/mailman/listinfo/genome
>   
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