Dear Marmam Readers, I am very pleased to announce the following publication:
Sílvia S. Monteiro , José V. Vingada , Alfredo López , Graham J. Pierce , Marisa Ferreira , Andrew Brownlow , Bjarni Mikkelsen , Misty Niemeyer , Robert J. Deaville , Catarina Eira , Stuart Piertney (2016). Major Histocompatibility Complex (MHC) class II sequence polymorphism in long-finned pilot whale (*Globicephala melas*) from the North Atlantic. Marine Biology Research doi: 10.1080/17451000.2016.1174266 Abstract Determining how intra-specific genetic diversity is apportioned among natural populations is essential for detecting local adaptation and identifying populations with inherently low levels of extant diversity which may become a conservation concern. Sequence polymorphism at two adaptive loci (MHC DRA and DQB) was investigated in long-finned pilot whales (*Globicephala melas*) from four regions in the North Atlantic and compared with previous data from New Zealand (South Pacific). Three alleles were resolved at each locus, with trans-species allele sharing and higher levels of non-synonymous to synonymous substitution, especially in the DQB locus. Overall nucleotide diversities of 0.49 ± 0.38% and 4.60 ± 2.39% were identified for the DRA and DQB loci, respectively, which are relatively low for MHC loci in the North Atlantic, but comparable to levels previously described in New Zealand (South Pacific). There were significant differences in allele frequencies within the North Atlantic and between the North Atlantic and New Zealand. Patterns of diversity and divergence are consistent with the long-term effects of balancing selection operating on the MHC loci, potentially mediated through the effects of host-parasite coevolution. Differences in allele frequency may reflect variation in pathogen communities, coupled with the effects of differential drift and gene flow. For an early view of this paper, please visit: http://www.tandfonline.com/doi/full/10.1080/17451000.2016.1174266 If you are unable to download the article, please contact me by email and I will be happy to send you a copy: s.monte...@ua.pt Best wishes, Silvia Monteiro ---------------------------------------- Postdoctoral researcher CESAM (Centro de estudos do ambiente e do Mar) University of Aveiro Portugal s.monteiro@ <http://www.bio.ua.pt/>ua.pt www.cesam.ua.pt/silvia.monteiro <http://www.cesam.ua.pt/index.php?tabela=pessoaldetail&menu=95&user=1040> Sociedade Portuguesa de Vida Selvagem/Portuguese Wildlife Society University of Minho Portugal www.socpvs.org
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