Hi Paulina, what version are you using? This looks like a bug that was
in 2.4.0. Perhaps you could revert to v2.3.1 or use the latest snapshot:
http://darlinglab.org/mauve/snapshots/2015/2015-02-25/MacOS/Mauve-snapshot_2015-02-25.dmg

I'm working to push a new release with these fixes ASAP but there are a
few other issues that need resolution first.

Best,
-Aaron

On Fri, 2015-03-20 at 14:04 +0000, Paulina Dmitrievna Pavinski Bitar
wrote:
> Good morning,
> Wondering if anyone has a suggestion for me. 
> I used progressivemauve to align 48 genomes and got a gibberish
> alignment because, silly me, I did not order my contigs first. 
> So re-ordered the contigs using Mauve Contig Mover (one at a time,
> using the same reference) and then tried to realign the 48 genomes
> with progressivemauve. 
> No luck. 
> After two hours progressivemauve exited with this error:
> 
> 
> 
> 
> Greedy BPE
> Scoring with scaled breakpoint penalty: 150573
> 1%..2%..3%..4%..5%..6%..7%..8%..9%..
> 10%..11%..12%..13%..14%..15%..16%..17%..18%..19%..
> 20%..21%..22%..23%..24%..25%..26%..27%..28%..29%..
> 30%..31%..done
> Arrived at 5 intervals
> Adding unaligned intervals
> addUnalignedIntervals yields 15 intervals
> Merging unaligned intervals
> Marbling gaps
> Propagating descendant breakpoints
> descendant 0(61) has 3 intervals
> descendant 1(64) has 1 intervals
> propagateDescendantBreakpoints yields 7 intervals
> Creating ancestral ordering
> Previous anchoring score: -1.79769e+308, new anchor score: 2.31866e+08
> Backing up alignment tree...
> propagating ancestral breakpoints
> recursive anchor search
> 0,0 have 62 new matches outside LCBs
> 1,0 have 77 new matches outside LCBs
> Caught signal 11
> Cleaning up and exiting!
> Temporary files deleted.
> 
> 
> 
> 
> 
> 
> Then I tried it again, no changes, just to see if maybe
> progressivemauve had simply crashed as it sometimes does for me for no
> apparent reason and got this error after two hours:
> 
> 
> Greedy BPE
> Scoring with scaled breakpoint penalty: 150573
> 1%..2%..3%..4%..5%..6%..7%..8%..9%..
> 10%..11%..12%..13%..14%..15%..16%..17%..18%..19%..
> 20%..21%..22%..23%..24%..25%..26%..27%..28%..29%..
> 30%..31%..done
> Arrived at 5 intervals
> Adding unaligned intervals
> addUnalignedIntervals yields 15 intervals
> Merging unaligned intervals
> Marbling gaps
> Propagating descendant breakpoints
> descendant 0(61) has 3 intervals
> descendant 1(64) has 1 intervals
> propagateDescendantBreakpoints yields 7 intervals
> Creating ancestral ordering
> Previous anchoring score: -1.79769e+308, new anchor score: 2.31866e+08
> Backing up alignment tree...
> propagating ancestral breakpoints
> recursive anchor search
> libc++abi.dylib: terminating
> 0,0 have 62 new matches outside LCBs
> 1,0 have 77 new matches outside LCBs
> 
> 
> Very similar but a little different. 
> I’m using the MCM output files totally unchanged. The data is the same
> but now in theory better suited for alignment since it’s been
> reordered. Other such errors people have mentioned are due to the
> format of the files. Could that be a problem and so late into the
> program – 2 hours? What else could it be? Would really love to see
> this work. 
> 
> 
> Thank you,
> Paulina
> 
> 
> 
> 
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by Intel and developed in partnership with Slashdot Media, is your hub for all
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news, videos, case studies, tutorials and more. Take a look and join the 
conversation now. http://goparallel.sourceforge.net/
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