Dear NMusers, Novartis is looking for candidates for the position of Director Pharmacometrics Scientist. Please apply through the link below. Director Pharmacometrics Scientist<https://sjobs.brassring.com/tgwebhost/jobdetails.aspx?partnerid=13617&siteid=5260&jobid=2438302&_ga=1.247987399.1774116789.1472736627>
Job ID 195382BR Posting Title Director Pharmacometrics Scientist Division PHARMA Work Location Cambridge, MA, or East Hanover, NJ, USA Functional Area Research & Development Job Type Full Time Job Description The Director Pharmacometric Scientist will: * drive pharmacometric strategy at Franchise and/or disease area level in (early/full) clinical development programs; * be responsible for driving the design and implementation of pharmacometric methodologies that help optimize drug development programs at the Franchise and/or disease area level; * serve as a consultant to the Franchise level leadership on strategic and regulatory pharmacometrics issues across all stages of development. The Director Pharmacometric Scientist role requires: * leading at a global level the planning, execution and delivery of modeling and simulation strategy for multiple indications and/or a disease area (or equivalent) within (early/full) clinical development; * expert knowledge and domain expertise in certain modeling areas and also strong therapeutic area expertise in 1-2 disease indications; * capable of developing collaborative relationships and strategic plans across programs in a therapeutic area; * responsibility for the design and implementation of pharmacometric methodologies that optimally address the research and development objectives on the assigned projects; * setting the strategy for addressing pharmacometric support for regulatory submissions, and directly influences drug development decisions with internal and external partners; * identifying the relevant development questions that would benefit from model-based methods and develop modeling plans to deliver meaningful and timely results clearly to development teams; * excellent communication and interpersonal skills and the ability to work independently and effectively on interdepartmental project teams; * good mentoring skills to help other associates and good collaborative skills with other quantitative disciplines including biostatistics. Minimum requirements * Ph.D. in pharmacology, biology, engineering, mathematics, statistics, or a field with significant modeling-related content (or equivalent Ph.D. / MD) required. * 8+ years industry experience required. * Candidates should have requisite expertise in quantitative pharmacology, strong hands-on modeling and simulation skills, and demonstrated impact on drug development through quantitative approaches experience. * Experience with mechanistic PKPD and/or system pharmacology modeling is preferred. * Rich hands-on experience with NONMEM, Monolix, R, Matlab and/or other modeling and simulation software is required. * Experience working within clinical project teams and contributing to (early/full-) clinical development strategy with good strategic understanding for applying quantitative analysis at the appropriate time. * Strong clinical, pharmacological and therapeutic knowledge of at least one disease area required. * Established track record of publications/presentations in pharmacometrics. * Experience in contributing to scientific improvement/change initiatives. * Excellent interpersonal and communication skills The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Gordon Graham Pharmacometrics I&D Franchise Leader Novartis Pharma AG Postfach CH-4002 Basel SWITZERLAND Phone +41 61 3246253 Mobile +41 79 3959364 Fax +41 61 3241246 gordon.gra...@novartis.com<mailto:gordon.gra...@novartis.com> www.novartis.com<http://www.novartis.com/>
