Dear NMusers, We have a position available for a PhD candidate at the Leiden Academic Centre for Drug Research, Leiden University, The Netherlands. Please see below, or visit: http://werkenbij.leidenuniv.nl/vacatures/phd-posities/16-380-jobs-leiden-university-phd-candidate-in-computational-clinical-pharmacometabolomics-to-enable-precision-medicine.html
The ideal candidate has experience with multivariate analysis of large biomedical datasets, modeling of time course data (mixed effect modeling), and some background in pharmacology/biomedical science. Thanks, Coen *PhD candidate in computational clinical pharmacometabolomics to enable precision medicine (1.0 fte) Vacancy number 16-380* Key responsibilities The primary aim of this project is to develop novel metabolomic biomarkers that may predict inter-individual variability to drug treatment response. To this aim you will analyze various “big” datasets derived from the Rotterdam study, a prospective population-based cohort study using state-of-the-art data science approaches. We will focus on developing novel methods to integrate various types of health data (e.g. patient characteristics, metabolomics, biochemical markers, drug concentrations) in order to derive novel insights into disease and drug action, and to improve drug treatment in individual patients. The project will be performed at the Systems Pharmacology Cluster, at the Leiden Academic Centre for Drug Research, Netherlands. Selection Criteria - Highly motivated individual with an interest in computational data science approaches, but also biology, medicine and drug research; - Master degree in the area of bioinformatics, applied biostatistics, biomedical- or (bio) pharmaceutical sciences, or bioengineering; - Experience in applying statistical modeling/machine learning approaches; preferably to biomedical problems; - Experience in a scripting language for data manipulation (preferably R); - Ability to work in a team and with good written English. Research at our faculty Our Faculty’s expertise spans the entire spectrum of science, ranging from Mathematics and Statistical science, Computer science and Data science, Astronomy, Physics, Chemistry and Pharmaceutical science to Biology and Environmental sciences. We are committed to provide meaningful, rigorous and quality academic experiences in a personalized environment with a cutting edge research infrastructure. Students can expand their academic horizons while deepening their expertise and knowledge in an array of disciplines. Our faculty members are inspired by a fascination with the unknown and the urge to enlarge our fundamental knowledge. At the same time they want to contribute to solutions for the big societal issues of tomorrow. The Leiden Academic Centre for Drug Research (LACDR) is a leading institute dedicated to world-class research and education in drug discovery and development. LACDR comprises a diverse and international team of approximately 150 researchers and is ideally located at the Leiden Bio Science Park, the largest life science cluster in The Netherlands. In the 2015 QS World University Ranking, the University of Leiden was listed number 9 globally in the area of Pharmacy and Pharmacology. For more information, see http://www.science.leidenuniv.nl. and http://workingat.leiden.edu/. For information on the Leiden Academic Centre for Drug research, please see http://www.lacdr.nl/. Terms and conditions We offer a full-time one year term position with the possibility of renewal based on need, funding and performance. Salary range from €2,174.- to € 2,779.- gross per month (pay scale P, in accordance with the Collective Labour Agreement for Dutch Universities). Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. Candidates from outside the Netherlands may be eligible for a substantial tax break. All our PhD students are embedded in the Leiden University Graduate School of Science (http://www.graduateschools.leidenuniv.nl/). Our graduate school offers several PhD training courses at three levels: professional courses, skills training and personal effectiveness. In addition, advanced courses to deepen scientific knowledge are offered by the research school. Diversity Leiden University is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups Information Enquiries can be made to dr. Coen van Hasselt, email coen.vanhass...@lacdr.leidenuniv.nl or prof. dr. Thomas Hankemeier, email hankeme...@lacdr.leidenuniv.nl. Applications To apply for this vacancy, please send an email to dr. Coen van Hasselt, email coen.vanhass...@lacdr.leidenuniv.nl. Please ensure that you upload the following additional documents quoting the vacancy number: • A letter with your motivation for this position • Curriculum Vitae • Name and contact information of 2 references Only applications received *no later than November 24, 2016* can be considered.
