Seeking a PhD level scientist with 5-12 years experience who is driven to
understand the PK and PD of novel drug candidates.
The successful individual for this role will be responsible for
investigating the pharmacokinetics, biodistribution, and PKPD relationships of
novel
therapeutics in preclinical models. They will then identify optimal candidates
for further development,
and for translating preclinical PKPD information to the clinic to ensure
appropriate
dose/regimen decisions. They will use state-of-the-art experimental and
quantitative approaches. The
candidate will be working in close partnerships across various functions
including
Biology, Bioanalytical Sciences, Tox and safety, biostats, Biomarkers, Clinical
Pharmacology,
and Regulatory. The candidate will represent the
department on cross- functional project teams as a PKPD representative and
present PKPD
results at cross- functional teams, department meetings, review committees, and
conferences. This role will provide the opportunity to lead teams and
potentially manage 1-2
direct reports.
Required: PhD in pharmacokinetics or related field with a Minimum of 5+ years
of relevant PKPD experience
and demonstrated impact on drug development and/or the PKPD scientific
Strong knowledge and experience in either oncology, immunology, and/or tumor
immunology are highly desired.
Strong knowledge and experience in PK and PK/PD of large molecule therapeutics
(e.g., monoclonal antibodies, bispecifics, fusion proteins, antibody-drug
conjugates,
etc.) are highly desired. Working knowledge of PK/PD software (e.g., WinNonlin,
NONMEM, ADAPT II, SimBiology, etc) and the ability to analyze and critically
assess
PK/PD data is essential.
Please contact me for more details at
brosebe...@cartermackay.com<mailto:brosebe...@cartermackay.com> or 315-415-4353
US or international candidates will be considered
[cid:1.1213385771@web31815.mail.mud.yahoo.com]
Brenda Roseberry
Division Manager-Scientific
Preclinical/Clinical--PK, Pharmacology, Pharmacometrics, Biomarkers
720-328-9526 - Office
315-415-4353 - Mobile
720-475-1176 - Fax
[cid:image001.png@01CBC1F8.25033B10]
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