Presenters: Wojciech Krzyzanski, Ph.D, Gilbert Koch, Ph.D, and Robert Bauer, 
Ph.D
The course will provide an overview of biological systems exhibiting delays, 
concepts of lifespan driven pharmacodynamic response, modeling of cell 
maturation, and nonlinear mixed effect lifespan models. Delay differential 
equations (DDEs) will be introduced and implemented in NONMEM pre-release 
version 7.5. The course will consist of both lectures and hands-on computer 
exercises. Source codes for DDE based PK/PD models and data will be provided to 
the participants.
This course, the Beginners/Intermediate course, and the Advanced Course are 
part of one series. Interested parties may register for the first two days, the 
third day, the fourth day or any combination of the three courses.
The fees for the course are as follows:

Industry - $700/per day
Academia/Government - $500/per day
Student - $300/day
A discount of 15% is available to groups of 3 or more participants from the 
same organization.
Contact Lisa Wilhelm-Lear at 
lisa.wilh...@iconplc.com<mailto:lisa.wilh...@iconplc.com> for more information 
and to register.

Deadline for registration is:  April 4, 2019



Lisa R. Wilhelm-Lear
Customer Service Lead
NONMEM / PDxPoP Software

Phone:  301-944-6771
Fax: 215-789-9549
lisa.wilh...@iconplc.com<mailto:lisa.wilh...@iconplc.com>
www.iconplc.com<http://www.iconplc.com/>
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