Scientist/Sr. Scientist opening in the US. Ideal location is in southern CA,
but remote will also be considered. Please email me at
brosebe...@cartermackay.com<mailto:brosebe...@cartermackay.com> for more info
* Analyze and interpret preclinical and clinical data. Study the effect of
diseases on animal and/or human physiology. Conduct research to further
understand the effects of healthy and disease states on drug absorption,
distribution, and elimination.
* Use mechanistic, physiologically-based pharmacokinetic (PBPK) modeling
and simulation approaches to integrate knowledge of pharmacokinetics,
pharmacodynamics, efficacy, safety, patient demographics, and
pathophysiological factors.
* Perform mechanistic absorption/PBPK modeling and simulation to address
objectives with client projects, including, but not limited to, FIH
predictions, formulation design/optimization, population simulations, and DDI
predictions.
* Construct and validate mechanistic mathematical models for description of
compound distribution in different tissues/organs in the body.
* Write study proposals, study reports, and/or white papers to clearly
describe model development and validation.
* Discuss software applications with clients and prospects on telephone or
in person.
* Share research findings by writing scientific articles and/or presenting
at scientific conferences.
Requirements:
* Ph.D. or Master's degree (or equivalent) in Pharmaceutical Science,
Biostatistics, Biomedical Engineering, or related fields.
* Minimum of three (3) years' experience as Scientist, Research Associate,
or related. (will consider at a higher level if someone is qualified)
* Experience should include performing PBPK modeling of distribution of
compounds in animals and humans. It should also include performing PBPK/PD
analyses of clinical data, including drug absorption, drug-drug interaction,
metabolic stability, clearance, and protein binding.
* Excellent oral and written communication skills.
* Demonstrates and communicates a positive attitude while interacting with
colleagues and clients at all levels.
* Must be able to multitask and have strong organizational skills.
* Self-motivated with ability to work with minimal supervision.
Job Location: southern CA or remote
[cid:1.1213385771@web31815.mail.mud.yahoo.com]
Brenda Roseberry
Division Manager-Scientific
Preclinical/Clinical--PK, Pharmacology, Pharmacometrics, Biomarkers
720-328-9526 - Office
315-415-4353 - Mobile
720-475-1176 - Fax
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