*ISoP NE - iPSP Symposium*

August 26, 2019 – Cambridge Innovation Center (CIC), Cambridge, MA

Full day: 8:30 am to 4:30 pm


New England Chapter of the International Society of Pharmacometrics
(ISoP-NE) is proud to host a one-day symposium focused on the integration
of Pharmacometrics and Systems Pharmacology (iPSP) being held at the
Cambridge Innovation Center in Cambridge, MA.

The goal is to raise awareness of the value created in linking primary
pharmacometrics with systems pharmacology and provide a forum highlighting
success stories in this space. The full-day agenda will include featured
presentations and short talks from our distinguished industry, academic and
regulatory speakers (see below) and the event will conclude with a happy
hour social at the MeadHall nearby. Please join us for a day of learning
and networking with your peers!


*Timing*

*Presenter: Topic*

8:30-9:00

*Registration and Breakfast*

9:00-9:15

Welcome

9:15-9:30

Cynthia Musante (Pfizer): *Introduction to iPSP*

9:30-10:00

Matthew Riggs (Metrum): *Open-Source and Open-Science to Progress the
Integration of Pharmacometrics and Systems Pharmacology*

10:00-10:30

Dhananjay Marathe (Merck): *Repurposing published models for drug
development applications*

10:30-11:00

*Coffee break*

11:00-11:30

Justin Earp (FDA): *Regulatory perspectives on model informed drug
development* – via WebEx

11:30-12:00

Sietse Braakman (MathWorks): *Using parameter non-identifiability and
global sensitivity analysis to inform the process of model calibration*

12:00-1:00

*Lunch*

1:00-2:00

Marc Horner (ANSYS): *Model Verification, Validation and Uncertainty
Quantification (VVUQ)* – via WebEx

2:00-2:30

Mirjam Trame (Novartis): *A case study for iPSP (integrated Pharmacometrics
and Systems Pharmacology) model concept*

2:30-3:00

*Coffee break*

3:00-3:30

Christopher Rackauckas (MIT): The Mathematical and Computational Basis of
Next Generation Pharmacometrics with Pumas.jl

3:30-4:00

Sarita Koride (Pfizer): *Evaluating the Role of Janus Kinase Pathways in
Platelet Homeostasis Using a Systems Modeling Approach*

4:00-4:30

*Panel discussion*

Post event

*Happy hour at MeadHall* – not a part of the event



Registration Fee:


Trainee/Student: $30*
ISoP Member: $60
Nonmember: $75


Registration includes breakfast, lunch and coffee provided. Ample
networking opportunities.
Registration is limited to 50 participants.  Register today!


*Register Here!
<http://clicks.memberclicks-mail.net/wf/click?upn=Jc-2BjM5zKS2k52JGCfRLuoSnm1-2F7M9FPt1gIt2Hk97ynQCqgHjDRiLdVt4iQsIdFujQdiPCyg0P-2FJcrKQU8SEkdcxWfiJ-2BYa-2FAf6g9nzt7Vcsx9yAd1uzO8-2F-2BM-2FBYJVsn_SpxrJVZ5zLLO9Wg1bkWUFQvxM68UnKCCnH5Aq8jdwAHHMBGj8tWnu52eKHWmfXJAleuNcAC8XwUNQWZAOFl8TYKHW5d-2BlF0XsqzYEywlCMtB5J9E0oWoYAxcCwUqs5NpW03eQD1BiKnwsSgTMeh-2BYxczv63jn5xTW8r-2FR6sd6EbK-2BdCnb8uQ0qiis15uQgUugnX0GnVbhSH-2BrvOO2OPJNkRCqa7PpqMtDptiN3CmCAoIgtOcjf-2FKRJbSSybCFBZoJ8cL0I0OkXtBcPHoeF4mWYDISBo9SmwRu6BquQJ2RbOPO-2BEGQvH-2BvZynSuwXovQ5JseooBdLQb-2BnlEAQNI7-2B0g-3D-3D>*

*nonmember trainees must use this code (isopnedisc) at checkout to receive
the discounted registration fee.

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