Dear colleagues,
We are pleased to offer a course “The 3rd advanced pharmacokinetic
pharmacodynamic course” in Chengdu, China August 16-19, 2020. For more
information and registration see below.
*The 3rd advanced pharmacokinetic pharmacodynamic course*
*COURSE OUTLINE*
Current approaches in the field of PK/PD involve development of models
based on mechanisms of drug action and their alteration of physiologic
processes. This course will provide a comprehensive overview of the
principles, techniques, and applications of PK/PD modeling with a partial
emphasis on modeling therapeutic proteins. Such modeling allows the optimal
design and interpretation of pharmacologic experiments that range from
molecular biology to human responses and can expedite the drug development
process. Lectures and examples from the recent literature will be provided
with course notes for each participant. Selected models or examples will
have a computer listing to show how to quantitate typical experimental
data. At the conclusion of this course, the biomedical scientist with basic
knowledge in pharmacokinetics will be able to understand the diverse array
of available PK/PD models and begin to apply them to experimental data and
to simulate anticipated drug responses.
*COURSE DIRECTION*
William J. Jusko, PhD
Dr. Jusko is SUNY Distinguished Professor and former Chair of
Pharmaceutical Sciences at the School of Pharmacy and Pharmaceutical
Sciences at the University of Buffalo and received the Doctor Honoris
Causae from the University of Paris Descartes in Sept 2015.
He supervises a research program on the pharmacokinetics and
pharmacodynamics of immunosuppressive, anticancer, and antidiabetic drugs.
and holds NIH grants in the areas of corticosteroid PK/PD and
mathematical modeling. He has authored over 600 publications, consults for
the FDA, NIH, and the pharmaceutical industry, and is listed in ISI Most
Highly Cited in Pharmacology.
Donald E. Mager, PhD
Dr. Mager is Professor of Pharmaceutical Sciences at the University at
Buffalo, State University of New York. He has been a fellow of the American
Foundation for Pharmaceutical Education and received the New Investigator
Award in Pharmacokinetics, Pharmacodynamics, and Drug Metabolism from the
American Association of Pharmaceutical Scientists in 2007. Dr. Mager has
served as a Visiting Professor at the Université Paris Descartes and on the
Advisory Committee on Clinical Pharmacology to the FDA. His research
invokes PK/PD systems analysis to characterize drug effects, with
particular interest in anti-cancer and immuno-modulatory pharmacotherapy.
*COURSE PROGRAM*
*Aug 16 Day 1*
13:00-17:00 Register & Reception
*Aug 17 Day 2*
08:20-08:30 1. Pr. HaiYan Li & Dongyang Liu: *Welcome*
08:30-09:45 2. W. Jusko: *Introductions: Overview, History & Highlights*
09:45-10:45 3. D. Mager: *Theory, Art, Practice of PK/PD*
10:45-11:00 04. Break
11:00-12:00 05. D. Mager: *Basic Pharmacology & Simple Direct Effects*
12:00-13:00 06. Lunch (take photo)
13:00-14:00 07. W. Jusko: *Biophase Distribution*
14:00-15:00 08. W. Jusko: *Basic Indirect Response Models*
15:00-15:15 09. Break
15:15-16:15 10. D. Mager: *Modeling Transduction *
16:15-17:00 11. W. Jusko *Slow & Irreversible Effects*
*Aug 18 Day 3*
08:00 Continental breakfast
08:30-09:30 13. D. Mager: *Review and Exercises I*
09:30-10:30 14. W. Jusko: *Chemotherapy Models*
10:30-10:45 15. Break
10:45-12:00 16. W. Jusko: *Complexities of Indirect Effects*
12:00-13:00 17. Lunch
13:00-14:00 18. W. Jusko: *Tolerance Models*
14:00-15:00 19. D. Mager: *Target-Mediated PK/PD *
15:00-15:15 Break
15:15-16:15 20. W. Jusko: *Disease Progression Models*
16:15-17:15 21. D. Mager: *Animal Scaling in PK/PD*
*Aug 19 Day 4*
08:00 Continental breakfast
08:30-09:30 23. W. Jusko: *Review and Exercises II*
09:30-10:30 24. D. Mager: *Antibody PK/PD*
10:30-10:45 25. Break
10:45-12:00 26. W. Jusko: *Modeling Drug Interactions*
12:00-13:00 27. Lunch
13:00-14:00 28. D. Mager: *Population PK/PD Models*
14:00-15:00 29. W. Jusko: *Computational Issues *
15:00-15:15 30. Break
15:15-16:15 31. D. Mager: *Systems PK/PD Modeling*
16:15-16:30 32. W. Jusko: *Summary*
*REGISTRATION INFORMATION*
*Course Location: *The course will be held at Chengdu. Specific information
to be determined.
*Fee: *Individual fee: RMB 9500(Asian countries only). This includes course
documentation, mid-session refreshments and lunches. Academia/Government of
the same organization can reduce the cost of one person for every three
registered people.The conference includes lunch only and no accommodation
is provided.
*Registration: *Please register ASAP in view of the limited course capacity
of 50 participants. Confirmation of registration will be returned upon
receipt with an invoice for course fees. Registration will not be final
until payment is received.
*Cancellations: *Cancellations with a full refund may be made until Jun 30,
2020. No refund is possible on cancellations received after this date.
*Hotel Information: *To be determined.
*Payment: *To be determined.
*Please contact:*
* DCTC-CPPO, *Email: cppo2...@126.com
* PUTH* Phone (86-10) -82265509
*Please scan the QR code below for registration:*
--
Best regards,
Xiaohan Wang
Drug Clinical Trial Center, Peking University Third Hospital
Tel(m): 19850855075,
Email: xiaohan...@yeah.net
