Here is a much-closer-to minimal example.
\setupregister [index] [maxwidth=4cm]
\setupdirections [bidi=on,method=two]
\starttext
.\index{Mairzy doats and dozy doats and liddle lamzy divey}
\placeindex
\stoptext
With the \setupdirections line removed, all is well. However, that line
is otherwise required. Setting bidi off around \placeindex is not an
option either, since some index entries require it.
--
Rik Kabel
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