Also, you might want to check out the gamm4 package. Ken On 04/21/14, Bert Gunter wrote: > See gam() and gamm() in the mgcv package. > > Cheers, > Bert > > Bert Gunter > Genentech Nonclinical Biostatistics > (650) 467-7374 > > "Data is not information. Information is not knowledge. And knowledge > is certainly not wisdom." > H. Gilbert Welch > > > > > On Mon, Apr 21, 2014 at 3:25 PM, John Sorkin > <jsor...@grecc.umaryland.edu> wrote: > > Colleagues, > > Is there any R program that will allow me to run a localized regression > > (e.g. smoothing spline) in the context of a random effects model? I have > > data on the growth of animals and want to create growth curves. I am not > > certain what shape the growth curve would take, so I would like to start > > with some sort of smoothed (but not "linear") regression to determine the > > shape of the growth curves. I would like to use a random effects model > > because I have multiple pairs of observations (age and weight) for each > > animal. If the shape of the growth curves appear to fit some parametric > > distribution, I will switch to a parametric model. > > Thank you, > > John > > John David Sorkin M.D., Ph.D. > > Professor of Medicine > > Chief, Biostatistics and Informatics > > University of Maryland School of Medicine Division of Gerontology and > > Geriatric Medicine > > Baltimore VA Medical Center > > 10 North Greene Street > > GRECC (BT/18/GR) > > Baltimore, MD 21201-1524 > > (Phone) 410-605-7119 > > (Fax) 410-605-7913 (Please call phone number above prior to faxing) > > > > Confidentiality Statement: > > This email message, including any attachments, is for ...{{dropped:14}} > > ______________________________________________ > R-help@r-project.org mailing list > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide http://www.R-project.org/posting-guide.html > and provide commented, minimal, self-contained, reproducible code.
-- Kenneth Frost Postdoctoral Research Associate - Dept. of Plant Pathology University of Wisconsin - Madison Lab: (608) 262-9914 Mobile: (608) 556-9637 kfr...@wisc.edu ______________________________________________ R-help@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/r-help PLEASE do read the posting guide http://www.R-project.org/posting-guide.html and provide commented, minimal, self-contained, reproducible code.