Dear CCP4ers,

The Institute of Pharmacology and Structural Biology (IPBS) in Toulouse, 
France, is seeking new group leaders. Details of the call are available at 
http://www.ipbs.fr/call2017. Please note that the application deadline is July 
15, 2017. Address inquiries related to the call at: recr...@ipbs.fr (not to 
me!).

Founded in 1996, the Institute of Pharmacology and Structural Biology (IPBS) is 
a leading research institute of the French National Centre for Scientific 
Research (CNRS) and the University of Toulouse. Located on the main Campus of 
the Université Toulouse III-Paul Sabatier in Toulouse, southwest France, the 
IPBS offers multidisciplinary education in the fields of Science, Health, 
Engineering and Technology, developing one of the most important scientific 
research clusters in France.
Our Institute is a world leader in the discovery, characterization and 
validation of novel important pathways and pharmacological targets in the 
fields of cancer and infectious diseases, through the use of molecular and 
cellular biology approaches, together with in vivo experiments. It conducts 
state-of-the-art research in structural biology, proteomics, biophysics, 
cancerology, immunology and microbiology (http://www.ipbs.fr). The IPBS brings 
together more than 250 scientists and supporting staffs, including more than 60 
national and international postdoctoral fellows and PhD students. The IPBS 
offers outstanding scientific and stimulating research environment and several 
cutting-edge core facilities with highly qualified staff. These include mass 
spectrometry and proteomics, macromolecular crystallography, liquid- and 
solid-state NMR, biophysical characterization of proteins and complexes, 
virtual screening, whole body, tissue and cellular imaging, flow cytometry and 
cell sorting in standard or BSL3 environments, single particle tracking and 
tethered particle motion analysis, and animal facilities.

In order to reinforce its research endeavors in an inspiring, collaborative and 
cutting-edge environment, the IPBS is seeking new talented junior group leaders 
addressing fundamental questions within the spectrum of its research fields. 
Young scientists of any nationality, at junior or midcareer level, and with an 
excellent track record of publications in internationally recognized journals, 
are encouraged to apply. International experience as well as capacity to 
interact with other research groups within the institute are highly 
recommended. Successful candidate(s) will be provided laboratory and office 
space for 5-8 people, a technical personnel and free access to the institute’s 
core facilities for a period of 2 years, together with a starting package for 
basic equipment and consumables. In addition, strong support will be provided 
from the IPBS to obtain tenured positions at CNRS, INSERM or the University of 
Toulouse. Outstanding candidates are expected to establish independent and 
vigorous national and international extramurally-funded research programs (ANR, 
ERC, etc.) that fit at least with one of the priority topics listed below. 
Researchers already holding a permanent position are also welcome to apply.

IPBS Priority topics
See full details for each topic at: http://www.ipbs.fr/call2017
• Tumor microenvironment – Cancer immunology - Interactions of immune cells 
with stromal cells, the extracellular matrix and/or other immune cells; immune 
response to cancer.
• DNA repair/chromatin remodeling in cancer - DNA damage response (DDR) in 
connection with cancer through epigenetics, transcriptional regulation, DNA 
repair pathologies, chromosomal translocations, DDR- based drug discovery, or 
tumor resistance to clastogenic agents.
• Pulmonary infections - Biology of bacterial respiratory pathogens, with a 
strong focus on mechanisms underlying pathogen’s persistence, drug resistance 
or tolerance within the host.
• Drug discovery & structural biology - Development of biological and chemical 
drugs of the future, with the aim of strengthening the pharmacological aspects 
of the IPBS research framework; characterization of drug-target interactions 
and mechanism of action; “hit to lead” strategies and new approaches for drug 
target deconvolution or vectorization will be favored. A particular attention 
will be given to candidates willing to create a group in biological NMR.

Application (about 5 pages in English) should include a cover letter describing 
previous research experience, an outline of the future research project, 
motivation for joining the institute and names and e-mail address of 3 
referees, together with an updated CV (including a complete list of 
publications). Application should be sent to recr...@ipbs.fr in a single PDF 
file named LASTNAME_FIRSTNAME_IPBS2017.pdf. Other formats will not be 
considered.

kind regards,
Laurent
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Laurent Maveyraud         laurent.maveyraud AT ipbs DOT fr
P I C T   ---  Plateforme Intégrée de Criblage de Toulouse
Université  Paul  Sabatier /  CNRS  /  I.P.B.S.  UMR  5089
Département     Biologie    Structurale   et   Biophysique
http://cribligand.ipbs.fr               http://www.ipbs.fr
205 route de Narbonne          31077 TOULOUSE Cedex FRANCE
Tél: +33 (0)561 175 435           Mob.: +33 (0)646 042 111
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