1.  TI=1000 actually separates the CSF/Grey/White peaks of the the histogram 
more evenly than TI=900ms (CSF and Grey too close) or TI=1100 (Grey and White 
too close).  I don’t understand why the FreeSurfer group has recommended 
TI=1100 as it wouldn’t seem to make things easier for their software.
  2.  I don’t remember the rational for the BOLD TE decision, but perhaps 
someone else does.

Peace,

Matt.

From: 
<hcp-users-boun...@humanconnectome.org<mailto:hcp-users-boun...@humanconnectome.org>>
 on behalf of HMZ <hmz...@163.com<mailto:hmz...@163.com>>
Date: Tuesday, August 1, 2017 at 8:05 PM
To: "hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>" 
<hcp-users@humanconnectome.org<mailto:hcp-users@humanconnectome.org>>
Subject: [HCP-Users] Questions about parameters in CCF protocols

Dear HCP team,

This is Meizhen Han at Center for MRI research in Peking University. I read CCF 
protocol carefully and have 2 questions in my mind. I would be very appreciate 
it if you could share some ideas with me.

1/ Why the TI in T1w was changed from 1060ms(LS in UMN/CMRR) to 1000ms(CCF)? Is 
there some significant difference between them? I find that TI can influence 
the contrast, and the TI recommended by freesurfer group is 1100ms, and the TI 
in HCP main project is 1000ms. From your experience, do you think TI=1000ms is 
better?

2/ TE in BOLD sequence(in CCF) is 37ms, while in common BOLD protocols TE is 
30ms usually. I think the echo should come at 30ms, and will decay  
significantly at 37ms. In my opinion, losing the edge of the k-space will blur 
the image and reduce SNR slightly. So why you choose TE = 37ms without a 7/8 
partial fourier to shorten it? I have tested similar protocol, and I find if I 
choose a 7/8 partial fourier, the TE can be around 30ms.

Any information and idea would help a lot! Looking forward to your reply.
Thank you very much!

Best wishes!

--
Meizhen Han
PhD Candidate
Center for MRI Research
Peking University
Beijing, China





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