[ccp4bb] PhD student position in Finland

Dear colleagues, We have a 4-year PhD student position for 2020-2023 open in my team. The project focuses on structural and functional characterization of human ADP-ribosyltransferases. For more details and application form please see the web application portal:

Re: [ccp4bb] Refinement of Occupancy in Refmac

Hi Deniz, yes you can do that, though I don't know right now how B-factors are taken into account when refining occupancies. Anyway, in i2 you have to go to the advanced tab. There is a place to put keywords in (text area). There you put the right combination of keywords for your special cases.

[ccp4bb] Refinement of Occupancy in Refmac

Hello, when I add an alternative conformation of a residue in COOT, I have to set the occupancy of both conformers, but Refmac5 won't touch these numbers. Can I tell Refmac to check for the best fitting occupancies (in the Windows version of CCP4i2)? With kind regards, Deniz Üresin Institute

[ccp4bb] Beamline Scientist position on PROXIMA 2A

Hi Everybody, Just as a reminder, we recruiting a Beamline Scientist (permanent position) on PROXIMA 2A at Synchrotron SOLEIL, which would be an excellent opportunity for a suitably motivated scientist. Please refer to the link below for more information:

Re: [ccp4bb] different residues as alternate occupancy?

Dear Guenter, yes look at crambin (pdbcode 1EJG). This crashes Coot until you add*   allow_duplicate_sequence_numbers() to $HOME/.coot.py in OSX or the appropriate place on Windows. For Windows, as there is no $HOME, Coot uses .coot.py or .coot-preferences/ directory for configuration - these

Re: [ccp4bb] different residues as alternate occupancy?

The structure of milk proteins obtained from in vivo-grown crystals from a viviparous cockroach could also serve as an interesting case: http://dx.doi.org/10.1107/S2052252516008903 best wishes Savvas > On 24 Jun 2019, at 16:03, Holton, James M >

[ccp4bb] 3rd International Meeting of HeCrA's young researchers

Dear all, We invite young scientists to participate at the 3rd International Meeting of HeCrA (Hellenic Crystallographic Association) for young researchers that will be held on 13-14 July, 2019 at the University of Patras in Patras, Greece. The meeting aims to reinforce European scientific

Re: [ccp4bb] different residues as alternate occupancy?

A classic case of this is crambin.  Residue 25 of 3nir. -James Holton MAD Scientist On 6/24/2019 1:00 AM, Guenter Fritz wrote: > Dear all, > > I am refining a multimer and mass spec data of the sample indicate > that there is a mixture of two variants which differ in one amino acid > residue.

[ccp4bb] Postdoc vacancy in cryo-EM of Gene Regulatory Complexes at Schalch Lab, University of Leicester

Dear all, Our position for a postdoc in structural biology is still open! Please spread the word or apply until 28th June, 2019 for an exciting challenge to study gene regulatory complexes. Great opportunity for hands-on cryo-EM at the Leicester Institute of Structural and Chemical Biology.

[ccp4bb] different residues as alternate occupancy?

Dear all, I am refining a multimer and mass spec data of the sample indicate that there is a mixture of two variants which differ in one amino acid residue. The density that we see is therefore most likely an average of both variants. I have created a pdb file with "alternate residues" each

[ccp4bb] PhD position at IOCB, Prague

PhD Position in Structural Parasitology at IOCB, Prague Job description A PhD position is open in Dr Sebastian Zoll‘s structural biology group at the Institute of Organic Chemistry and Biochemistry (IOCB) in Prague. The group is interested in understanding the structural basis of interaction