Re: [ccp4bb] Linux Distro for setting up workstations - Is CentOS still a good choice?

2021-02-19 Thread Kay Diederichs
completely agree! There are actually several potential CentOS replacements, if needed. Kay On Fri, 19 Feb 2021 13:47:25 -0800, Dale Tronrud wrote: >For what it's worth, CentOS 7 will continue to be supported to the >middle of 2024. That will give you time to see how all this shakes

Re: [ccp4bb] Linux Distro for setting up workstations - Is CentOS still a good choice?

2021-02-19 Thread Dale Tronrud
For what it's worth, CentOS 7 will continue to be supported to the middle of 2024. That will give you time to see how all this shakes out. https://wiki.centos.org/About/Product Since Red Hat Linux is founded on open source software anyone can fork a new Linux distribution based on it,

Re: [ccp4bb] Linux Distro for setting up workstations - Is CentOS still a good choice?

2021-02-19 Thread Ethan A Merritt
Well, since you ask... I prefer, and recommend, Mageia. Second choice SuSE. I find that the default configuration and choice of packages on these are a better fit to my use in development and computation both on my lab machines/servers and on my desktop/laptop. cheers,

[ccp4bb] Linux Distro for setting up workstations - Is CentOS still a good choice?

2021-02-19 Thread Matthias Zeug
Hi all, I just came across the (already quite old) news that Red-Hat switches their support-policy for CentOS to a rolling preview model (replacing CentOS Linux by CentOS Stream): https://www.zdnet.com/article/why-red-hat-dumped-centos-for-centos-stream/

Re: [ccp4bb] Contagious, Self-Distributing "Vaccines?"

2021-02-19 Thread Tim Gruene
Dear Jacob, you cannot kill a virus. It is not alive, but a complex chemical compound that interferes with the chemistry of the host. So why don't you work on the part of your conept over the week-end and present the concept? Cheers, Tim On Fri, 19 Feb 2021 12:55:32 -0500 Jacob Keller wrote:

[ccp4bb] postdoctoral positions at the NIH in cryo-EM, in vitro reconstitution and single molecule fluorescence microscopy

2021-02-19 Thread Antonina Roll-Mecak
I am advertising for two postdoctoral positions in my lab. Our overall goal is to understand the structure and function of tubulin modification enzymes and microtubule effectors using a combination of cryo-EM, in vitro reconstitution and protein engineering. One postdoc position will be ideal for

[ccp4bb] (Senior) scientist Antigen Production at the Institute for Protein Innovation in Boston, USA

2021-02-19 Thread Rob Meijers
Dear colleagues, the Institute for Protein Innovation (IPI) is developing human synthetic IgG antibodies for the human cell surfaceome, with a special emphasis on cell surface receptors involved in neuronal development, immunotherapy and cancer. We are looking for a structural biologist with

Re: [ccp4bb] Contagious, Self-Distributing "Vaccines?"

2021-02-19 Thread Jacob Keller
I don't think seeing the big picture resolves, or even addresses, the question of possibly using a live vaccine. Some big-picture considerations favor each side. The concern of mutation is a grave one, and an unknown. I would point out, however, that the same considerations apply to the wild

Re: [ccp4bb] Rigaku CrystalTrak Web not working

2021-02-19 Thread Newman, Janet (Manufacturing, Parkville)
I posted this offline to Pavel, but maybe there are more people out there who might find it useful? Hi Pavel, We have built and use See3, which is a replacement for CTweb that doesn't use flash. It still uses the CM (Crystal) database. If you are interested you can check it out (it would be

Re: [ccp4bb] Rigaku CrystalTrak Web not working

2021-02-19 Thread Thomas, Leonard M.
So I just checked ours and you should be able to access the interface unless your institution is blocking it. You can not look at individual drops but if you go to the XXL in the Thumb drop down then you can at least see if anything maybe in the drops. And as mentioned looking locally is

Re: [ccp4bb] Challenging Molecular Replacement

2021-02-19 Thread Muhammad Bashir Khan
Thank you all for the nice suggestions. Regards; Bashir On Tue, Feb 16, 2021 at 1:09 PM Randy John Read wrote: > Yes, I agree with Eleanor. But if there’s translational NCS, either the > off-origin Patterson peak is below 20% of the origin peak so that Phaser is > missing it, or perhaps

Re: [ccp4bb] Rigaku CrystalTrak Web not working

2021-02-19 Thread Pavel Mader
Hi Johannes, just making sure that there is no misunderstanding. I am currently working in Dr. Frank Sicheri lab at Mount Sinai Hospital in Toronto, ON, Canada. Is this the local installation you are talking about? I am just using my Czech email account, since I have the CCP4BB already set up

[ccp4bb] RS refinement of cyclic peptides

2021-02-19 Thread Paul Emsley
Jan Abendroth wrote: does anyone have any hints on how to real space refine cyclic peptides with unusual amino acids in Coot? A good example are DNA-sliding clamp proteins in complex with the cyclic peptide Griselimycin, eg. PDB code 6PTV. In Coot I load the ligand description cif files for

Re: [ccp4bb] Contagious, Self-Distributing "Vaccines?"

2021-02-19 Thread Mike S
Since we've already gone down this rabbit hole (pun intended), there's been quite a bit written in the last year about the 'value of a statistical life' and pandemic insurance.

Re: [ccp4bb] Rigaku CrystalTrak Web not working

2021-02-19 Thread Arnaud Basle
Hi Pavel, We have the same problem. We no longer use the web interface. We connect to the server with remote desktop protocol and run crystaltrack software remotely. While no ideal it works. If you can run a Windows 7 machine on your network and connect to the server you can install

Re: [ccp4bb] Rigaku CrystalTrak Web not working

2021-02-19 Thread Johannes Cramer
Hey Pavel, afaik our local installation of the software still works. So if going there physically is an option for you, you can try that. Cheers, Johannes Am Do., 18. Feb. 2021 um 18:21 Uhr schrieb Pavel Mader < mader.pa...@seznam.cz>: > Hello everyone, > > is there anyone else, who is using

Re: [ccp4bb] Contagious, Self-Distributing "Vaccines?"

2021-02-19 Thread Eleanor Dodson
I have been following this discussion with interest, without having any informed opinions to throw in.. (Except as the daughter of an Australian farmer I still see myxomatosis as a blessing - my father said in his youth to make a living he spent 10months of every year trying to control the rabbit

Re: [ccp4bb] Contagious, Self-Distributing "Vaccines?"

2021-02-19 Thread Robbie Joosten
Hi Tim, Very good points. The big picture is hard to grasp and we end up taking political choices rather than anything else. I'm very glad that we can outsource these choices to others every four year here. Lockdowns may save lives in the here and now, but the global economic damage makes

Re: [ccp4bb] Contagious, Self-Distributing "Vaccines?"

2021-02-19 Thread Tim Gruene
Hi Jessica, one comment: death cannot be prevented. It is a certainty as soon as you are born (well, 9 months before). While this seems an obvious subtlety, many of the current measures seems to be influenced by the (probably unconscious) belief one can defeat death. We can only reduce the risk