A quote comes to mind (I cannot resist) :
"Now, my own suspicion is that the universe is not only queerer than we
suppose, but queerer than we can suppose [...]"
-J. B. S. Haldane
"Possible Worlds"
in Possible Worlds and Other Essays (1927), p. 286
I absolutely agree with Guenter. This non experts speaking wrong things is
increasingly happening nowadays. Thanks Guenter, for pointing this out. A
theory unless it is given experimental data derived evidence it is still a
prediction (just like weather prediction, unless it is realised in the
We are getting the same feeling from discussions with (non-structural)
biologists around us.
I also agree that AlphaFold models are a great tool but they do not tell
everything and cannot exactly replace experiments.
Is the development mainly in the hands of journals' reviewers...?
Best,
Jan
Dear all,
taking AlphaFold models for " true" experimental structures seems to
become a serious problem.
I am just returning from a meeting (not a structural biology meeting)
and saw one model after other. And the non-structural biologist used
terms like "we calculated a structure" or "a
Dear all
I would like to draw your attention to the two faculty positions in Protein
Biochemistry and Biochemical Engineering/bioprocess at the University of
Limerick. Closing date for applications is the 11th of May
https://my.corehr.com/pls/ulrecruit/erq_jobspec_version_4.display_form
Best
Dear all
The ESRF and EMBL Joint Structural Biology Group, with the support of EU
project Streamline, is organizing a workshop on sample preparation, data
collection and data processing for Ambient Temperature Crystallography.
ESRF and EMBL have been laying the groundwork for the future
