Good morning, Everyone,
We are trying to dock two small molecule ligands into a big active site
of the enzyme. We tried to dock two simultaneously using Autodock Vina,
but one always got kicked out. Is there a way we can dock both ligands?
Thanks for your suggestions.
Best,
Haiying
afterwards
Phil Jeffrey
Princeton
--
Haiying Bie, Ph.D.
Postdoc Fellow at Michael James lab
4-29 Medical Science Building
Department of Biochemistry
University of Alberta, Edmonton, T6G 2H7
Hi, all
I have encountered the high Rwork/Rfree values. Here is the story:
The glycosylated native protein structure is solved in the P212121
with unit cell parameters of 72.6, 78.0, and 112.5 and the all
solution statistics are perfectly fine. I am trying to crystallize and
solve the structure
