[ccp4bb] Structural Biology Post available at Evotec

Dear All, A position is now available at EVOTEC for a Senior Scientist in Structural Biology. Please do not email me directly about this position but use the link below for applications. Best regards, Paul

[ccp4bb] Position Available at Evotec

Dear All, Please note I've had several emails from prospective applicants regarding failure of our weblink on the advert. Could all applicants please repost applications through this weblink below: https://evotecgroup.wd3.myworkdayjobs.com/Evotec_Career_Site Best wishes, Paul..

[ccp4bb] 2 crystallography posts available at Evotec

Dear All, There are two senior scientist posts available at Evotec in Abingdon, UK. Please do not contact me directly for application, please use the online recruitment weblink at the base of this email. Evotec is a leader in the discovery and development of novel small molecule drugs with

[ccp4bb] Group Leader Position available at Evotec

Dear All, Evotec is expanding and is looking to recruit a Group Leader. Please do not contact me directly but liaise with the Human Resources team though our website. Best wishes, Paul.. AB GL SB Sept18 - Group Leader, Structural Biology Posted: 21/09/2018 15:08 Start Date: Not Available

[ccp4bb] X-ray system available

Dear CCP4bb readers, We are in the process of decommissioning our in-house X-ray source and would like to offer it to the community. The device is showing its age based on the technology, but hopefully somebody could make use of it. In brief, the equipment is a Rigaku 007-HF generator with two

[ccp4bb] Job Opportunity

Dear All, I have an opportunity for somebody to join my team in structural biology at Evotec. All applications must be made through our website and please address any questions regarding the application process to humanresources-abing...@evotec.com

Re: [ccp4bb] how to reduce protein solubility

Hi Francesca, You could try using reductive methylation, this has always lead to a loss of solubility (and protein!) in my experience­. Jena bioscience and Hampton research sell kits. Best regards, Paul.. [EvotecLogoMail] Paul A. McEwan Ph.D. Principal Scientist, Structural Biology +44. (0)1235

[ccp4bb] Industrial Protein crystallographer post available

Dear CCP4bb members, We have an exciting opportunity for somebody to become a member of our expanding structural biology unit to support development of new drugs, biopharmaceuticals and biotechnologies. Please only apply via the careers page on our website www.evotec.comhttp://www.evotec.com

[ccp4bb] crystallography position open at Evotec

Dear All, We have a great opportunity for somebody to join the structural biology team at Evotec as a crystallographer. The closing date for applications is the 31st March. Please make applications via the website as listed in the advert below. Best regards, Paul..

[ccp4bb] FW: [ccp4bb] disulfide engineering

Rather than looking at anti-DTT it is more important to set up an appropriate redox system. This can be a combination of reduced and oxidised glutathione or cysteine. If you check some of the commercial protein refolding screens this should give you an idea about relative concentrations. Best

[ccp4bb] small lysozyme crystals

Use the 15 minute protocol from the Hampton Research catalogue/website. They're normally quite small and easy to cryoprtect with a little glycerol. Size can also be varied by playing with the salt concentration (slightly higher [NaCl]giving more but smaller xtals) Paul..

Re: [ccp4bb] Structural importance of ordered water?

Title: Re: [ccp4bb] Fw: Re: [ccp4bb] Structural importance of ordered water? Some work has been done on collagen regardingits hydration structure: (crystal data) Bella,J.Brodsky, B. Berman, H.M.. Structure (3), 893-906 1995 (NMR) Peto, S. Gillis, P. Henri, V.P.. Biophys J. (57), 71-84, 1990