Hi Derek,
That brings back memories. I am pretty certain that is the myoglobin crystal
that was already on Benno's shelf at Brookhaven when I went there in 1980 to
collect my oxymyoglobin neutron data. It would the metmyoglobin crystal Benno
got the early neutron data from. He just kept it
I once grew an oxymyoglobin crystal 1 cm long for neutron diffraction at
Brookhaven. I was very proud of it, but when I got to Brookhaven I was told it
was too big for the beam (!) so I had to use a much smaller one of only 8 mm**3
(Nature 292:81-82 (1981). I still have a few left over that
-crystallisation and crystal soaking methods are
essential. Experience with surface plasmon resonance and small molecule
library screening will be advantageous. The post will be based in the
laboratory of Professor Simon Phillips
http://www.rc-harwell.ac.uk/directors.html at RCaH (adjacent
I take the point about a tendency in those days to apply sigma cutoffs to get
lower R values, which were erroneously expected to indicate better structures.
I wonder how many of us remember this paper by Arnberg et al (1979) Acta Cryst
A35, 497-499, where it is shown for (small molecule)
Dear Tim,
Interesting discussion, and I agree with your last description of the issues.
When I started playing with this for oxymyoglobin [J. Mol. Biol. 142, 531-544
(1980)]
it seemed immediately apparent (i.e. by thinking about it before starting to
write programs) that the simple Babinet
, of course, you cannot do this
and the maps are in units of scattering density.
Simon Phillips
---
| Simon E.V. Phillips
synchrotron. The positions are funded
by a five-year MRC research grant to Simon Phillips and Steve Carr to work on
structural studies of complexes involved in Holliday junction resolution.
RCaH will be equipped to a high standard for structural biology, and will also
house the Oxford Protein
. The positions are funded by
a five-year MRC research grant to Simon Phillips and Steve Carr to work on
structural studies of complexes involved in Holliday junction resolution. RCaH
will be equipped to a high standard for structural biology, and will also house
the Oxford Protein Production
Dear CCP4BBers,
With apologies to non-UK crystallographers (to whom it is not relevant
so they should read no further).
Just to let you know that there are opportunities for grant and
fellowship applications from researchers wishing to work in the Research
Complex at Harwell (RCaH). This is a
