Dear Pavel,
sorry for the late reply.
You might look at the tyrosine-phenol lyase structures, in which a small
domain in one of the two crystallographically independent protein subunits
is discretely disordered, PDB IDs 6DUR and 6ECG.
Actually, modeling the small domain in the two discretely
Crambin (quick search for “Martha Teeter” and “Crambin” should yield
dividends)? There are some very high resolution structures of that with
multiple conformations.
Harry
> On 23 Aug 2022, at 23:02, Pavel Afonine wrote:
>
> Dear community,
>
> I’m looking for an example of a crystal
Hi Pavel,
I guess one which might a very good example for your requirements is Urease
from sporosarcina pasteurii. The active side is covered by a “mobile flap”
(chain C, residues 320- 340). Depending on the active site bound molecule
(substrate analogue, inhibitor, …) the flap can occur in
Dear Pavel,
Recently we determined the structure of a fusion protein with 2.5 chains
in the AU in P3(2)21 (I posted this case in the ccp4bb). The protein
forms a pentamer with one chain sitting on the 2-fold. I refined it in
P3(2) with 4 well defined chains and the 5th chain having two
Dear Pavel,
One of my colleagues solved this structure (
https://www.rcsb.org/structure/2gn0). I watched in awe while he built and
explained the structure.
Hopefully the structure is useful
-Bharath
On Tue, Aug 23, 2022 at 6:03 PM Pavel Afonine wrote:
> Dear community,
>
>
>
> I’m looking for
Dear Pavel,
I have seen this in very high-resolution models of triclinic lysozyme but I
don't remember the PDB ids.
Best wishes,
Kay
On Tue, 23 Aug 2022 15:02:07 -0700, Pavel Afonine wrote:
>Dear community,
>
>
>
>I’m looking for an example of a crystal structure where a large group of
Hello Pavel,
You may want to have a look at PDB structure 6YCR: the macrocyclic
peptide inhibitor is modelled as two conformations. The entire peptide.
HTH,
Fred.
On 8/24/22 00:02, Pavel Afonine wrote:
Dear community,
I’m looking for an example of a crystal structure where a large group
Hi Pavel,
There are a number of DNA structures that are complete made up out of alternate
atoms.
Cheers,
Robbie
> -Original Message-
> From: CCP4 bulletin board On Behalf Of Pavel
> Afonine
> Sent: Wednesday, August 24, 2022 00:02
> To: CCP4BB@JISCMAIL.AC.UK
> Subject: [ccp4bb] ISO
Dear community,
I’m looking for an example of a crystal structure where a large group of
atoms (as large as a whole chain or even a domain) have more than one
distinct conformation that would require modeling of such chain/domain as
more than one individual copy, with each copy having partial
