[ccp4bb] Omit maps in cases of NCS?

[Francis E Reyes]

How does one calculate a simulated annealing omit map in cases of non  
crystallographic symmetry? The omit map is being used to identify the  
presence and configuration of a ligand and surrounding residues. The  
omit region therefore will contain the ligand and residues within  
hydrogen bonding contact. The residues obey NCS. The refinement will  
not include NCS ( refinement at 2.0 A with ncs leads to worse r/rfree  
statistics).

 with that said should the omit region include all NCS related  
molecules or just one? If the former, does one average the sa omit  
mAps to present in a figure?

Thanks,
FR