[ccp4bb] more on dimerization interface analysis

2007-11-29 Thread Andreas Förster
Dear all, Karen question reminded me that I have one also. I study a protein that homodimerizes via a long helix. A number of homologs exist. They all dimerize, but the structure is only known of the first. Homology is high enough that I can easily thread the homologs' sequences onto the

Re: [ccp4bb] more on dimerization interface analysis

2007-11-29 Thread David Briggs
Hi Andreas, This maybe a little ott, but the Rosetta suite of modelling programs will do docking with some minimisation and side chain optimisation. You can also enforce symmetry. http://www.rosettacommons.org/ http://depts.washington.edu/bakerpg/ It is free to academics and runs on most