Hello all,
I would appreciate it if you could distribute this flier to potential
applicants.
Thank you,
Mark Walter
Post-doctoral position: Structural Biology of Cytokine-Receptor
Signaling
A Post-doctoral position is available immediately to study the structure
and function of cytokine receptor complexes that play essential roles in
the development and control of the adaptive immune response. The
inter-cellular communication provided by these molecules is controlled
by a dazzling array of protein-protein interactions that our lab is
unraveling. We also study the structure and function of virally encoded
proteins produced by herpes and poxviruses that target the IL-10 family
and allow the viruses to escape elimination by the immune system.
Understanding the competing molecular strategies used by the host and
virus to activate or deactivate the immune system may to lead novel ways
of controlling chronic inflammation and/or improving the detection and
elimination of persistent viral infections. The lab performs the
techniques required to answer mechanistic questions about molecular
recognition, viral immune evasion, and cell signaling including protein
biochemistry, X-ray crystallography, surface plasmon resonance,
isothermal titration calorimetry, computational and bioinformatic
approaches, and structure-based functional assays in cells.
Applicants are expected to be proficient in molecular
biology, protein expression (multiple systems is a benefit), and protein
purification methodologies. Experience in X-ray crystallography, or
other structural or biophysical science (e.g. NMR, SAXS, etc), is a
plus. Interested applicants should send a CV, statement of research
interests, and list of references to:
Dr. Mark R. Walter
Department of Microbiology
University of Alabama at Birmingham (UAB)
RM 144 CBSE
1025 18th Street South
Birmingham, AL 35243
wal...@uab.edu
