*Team Leader Protein Crystallography*
Jealott's Hill, Bracknell, Berkshire, UK We are seeking a highly talented and motivated crystallographer who is enthusiastic about working across the range of protein crystallography activities covering a wide variety of biological systems. The successful candidate will have a strong background in protein production and crystallization as well as x-ray data collection, structure refinement and validation. Computational and molecular modelling skills are a plus. The successful candidate will need to demonstrate flexible teamworking and a tenacious approach to delivering structural solution outputs to projects. Excellent oral and written communication skills and the ability to translate structural knowledge to a meaningful output for multidisciplinary project teams are highly desirable qualities for this position. *Responsibilities* • Lead the protein crystallography team and provide protein crystallography support for research projects • Maintain a strategic overview of projects requiring structural biology support; engage and communicate effectively with stakeholders to ensure optimal use of resources • Guide molecular biology and protein purification for crystallography • Carry out crystallization, x-ray data collection, structure determination and refinement of proteins and protein-ligand complexes • Communicate results to chemists, computational chemists and cross-disciplinary project teams so that results make an impact in structure-based design and understanding of SAR of new leads • Develop and maintain high quality standards for in-house structure data and crystallographic computing procedures • Responsible for organization of own and team's laboratory work including ordering laboratory supplies and equipment • Formal and informal teaching and coaching of other lab staff and trainees *Experience required* • PhD in macromolecular crystallography/structural biology plus 5 years industry experience or equivalent • Demonstrated experience in protein crystallization, structure determination, refinement and validation • Knowledge of chemistry, molecular structure and protein-ligand interactions • Knowledge of software for protein structure solution and refinement • Knowledge of protein production *About Syngenta* Syngenta is one of the world’s leading companies with more than 27.000 employees in over 90 countries dedicated to our purpose: Bringing plant potential to life. Through world-class science, global reach and commitment to our customers we help to increase crop productivity, protect the environment and improve health and quality of life. For more information about us please go to http://www.syngenta.com/. For a full job profile and to apply to this position, please visit http://www.syngentajobs.com/Taleo_apply.html?CountryCode=2gb&lang=en&location=23236270036668&portal=101430233 - job number 14006122 Application deadline is 16th June. I am happy to answer informal questions about the position (please use the e-mail address below), but if you wish to apply you must go through the Syngenta Jobs website linked above. Thanks, Daniel Kloer Head of Protein Analysis and Computational Chemistry Syngenta daniel.kl...@syngenta.com
