-Caveat Lector-

This seems a bit timely.

Hilary


-----Original Message-----
From: Dan S <[EMAIL PROTECTED]>
To: isml <[EMAIL PROTECTED]>
Date: Tuesday, January 05, 1999 7:53 PM
Subject: [InTheShadows] Thai scientists to clone rare white elephant


>From: Dan S <[EMAIL PROTECTED]>
>
>From:
>http://www.exn.ca/html/templates/htmlpage.cfm?ID=19990104-57&Parent=Science
>-
>Thai scientists plan to clone rare white elephant   January 4, 1999
>
>Scientists in Thailand are hoping to bring back a royal elephant that
>died more than a hundred years ago. They hope to clone the white
>elephant from its remains which have been preserved in alcohol for
>posterity.
>
>"If possible, we scientists hope to clone this elephant since it is the
>best one ever found in the country," Chisanu Tiyscharoensri at Mahidol
>University's Institute of Science and Technology for Research and
>Development in Bangkok told the Bangkok Post.
>
>"Entirely white" and "extremely rare", the animal belonged to the 19th
>century monarch, King Rama III, who ruled Thailand from 1824 to 1851.
>
>The elephant is Thailand's national symbol, but deforestation and
>poaching are causing its numbers to dwindle. The white elephant –
>characterized by its lighter-coloured skin – is rare. Believed to bring
>good luck, all white elephants in Thailand are automatically the
>property of the Royal family.
>
>Inspired by Japanese scientists who are attempting to resurrect the
>mammoth, the team of scientists at Mahidol University has already
>succeeded in cloning a cow and hope their ten-year project will bring
>back a truly white-coloured elephant.
>
>But, their hope may remain just that – hope.
>
>"No one has ever succeeded in reconstructing a cell from preserved DNA,"
>says Dave Evans, acting chair of molecular biology and genetics at the
>University of Guelph. "People have been suggesting that they might get
>mammoths back from [the remains of] frozen mammoths. But, even with
>frozen cells, they're so badly damaged by the freezing, the basic
>chromosomal structure is all degraded."
>
>And alcohol would degrade the genetic material required for a
>successful  cloning too, says Evans.
>
>"Alcohol is used as a preservative because it's a dehydrating agent,"
>says Evans. He can't see how the nucleus (which contains all the genetic
>material) of any of the elephant's cells could remain intact when
>alcohol kills the lipid membranes which make the nucleus.
>
>While Evans points out that scientists have recovered some genes from
>old DNA and have even sequenced them from the frozen mammoths which
>roamed the Earth tens of thousands of years ago, he predicts it will be
>a long time before we're able to recover the nucleus required to clone
>an animal from such an old specimen.
>
>
>--
>
>[EMAIL PROTECTED]
>
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