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From: Bill Kingsbury <[EMAIL PROTECTED]>

http://news.bbc.co.uk/hi/english/health/newsid_503000/503781.stm


 Soya beans linked to developmental damage

 Soya beans may affect foetal development

 BBC News Online - Health
 Wednesday, November 3, 1999

 Pregnant women who eat a diet high in soya beans may
 increase the risk of long-term developmental damage in
 their children, researchers have found.

 Soya beans contain compounds called phytoestrogens or
 isoflavones, that have been found to mimic the effects of
 the female sex hormone oestrogen.

 These effects may help to prevent a range of conditions
 including the unpleasant symptoms of the menopause.

 But scientists at the Third International Symposium on the
 Role of Soy in Preventing and Treating Chronic Disease in
 Washington DC were told the impact on foetuses and children
 could be negative.

 A team from Cedars-Sinai Medical Center presented data from
 two studies - one on animals and one on humans - to the
 conference.


 Organising tissue development

 Dr Claude Hughes, director of the Center for Women's Health
 at Cedars-Sinai Medical Center, said sex hormones appeared
 to play an important role in organising the development of
 tissues early in life.

 He said: "These hormones influence the way the brain is
 organised, the way the reproductive organs and cells
 develop, even the way immune function develops.

 "Therefore, if mom is eating something or has in her body
 fat something that can act like sex hormones, it is logical
 to wonder if that could change the baby's development."

 The researchers analysed amniotic fluid samples of 54
 pregnant women from the Los Angeles area.

 They found that about 80% of the foetuses were exposed to
 phytoestrogens at levels up to 180 times the norm.

 The amniotic fluid samples were taken during routine
 amniocentesis between 16 and 20 weeks of gestation - after
 a baby's organs have formed but during a critical stage of
 development.

 The researchers tested the impact of exposure to
 phytoestrogen by feeding them to pregnant rats at a similar
 stage of their pregnancy.


 'Masculinising' effect

 The phytoestrogen had a "masculinising" effect on both the
 male and female rat foetuses.

 Male rat pups also experienced early onset of puberty.

 Dr Hughes said the rat experiment was likely to give some
 indication of the effect of phytoestrogens on human
 foetuses.

 He said: "There is no reason to assume that there will be
 gross malformations of foetuses but there may be subtle
 changes, such as neurobehavioral attributes, immune
 function, and sex hormone levels."

 "There are many long-term health questions that come about
 when the little clocks in our heads are changed. There may
 be subtle things occurring and we don't know it.

 "Or it could be that humans are much more resistant to
 these effects than are other animals, and this is not an
 issue. We will not know until we get the data."



~~~~~~~

http://news.bbc.co.uk/hi/english/health/newsid_613000/613396.stm


 Sex drive warning to vegetarians and elderly

 BBC News Online - Health
 Friday, 21 January, 2000

      The decrease in bioavailable testosterone can then
      result in declines in sexual function and red cell
      mass, and contribute to the loss of bone density
              --Dr Christopher Longcope

 Elderly and vegetarian men are being warned about the effect
 of low protein diets on their sex lives in later years.

 Researchers say people who do not eat enough protein are at
 risk of low testosterone levels which can cause a decline in
 sexual function as well as muscle loss, reduced red blood
 cells and damage to bones.

 People who do not eat meat are particularly at risk, because
 animal products are good sources of high biological value
 proteins.

 As well as vegetarians and vegans who choose not to eat
 animal products, the elderly are known to eat less meat
 because of loss of appetite in later years and difficulty
 with chewing.

 Dr Christopher Longcope, of the University of Massachusetts
 medical school, says his latest findings mean the elderly in
 particular should be counselled about the importance of
 eating enough protein.

 He found that low protein diets lead to increases in sex
 hormone-binding globulin in older men, which reduces the
 availability of testosterone.


 Sex hormone levels

 Dr Longcope and colleagues looked at globulin levels in 1,552
 men aged between 40 and 70. Protein and fibre intake levels
 were significant contributors to sex hormone levels, as were
 age and body mass, they said in The Journal of Clinical
 Endocrinology and Metabolism.

 He said: "The decrease in bioavailable testosterone can then
 result in declines in sexual function and red cell mass, and
 contribute to the loss of bone density."

 And high protein diets could increase the available
 testosterone, though further research into this areas was
 needed, he said.

 Denise Parish, a dietician at the University Hospital of
 Wales in Cardiff, said it was known that low protein diets
 caused muscle loss, but the link with testosterone had not
 previously been made.

 She added: "In the elderly population, people tend to have
 lower protein intake because of poor denticulation, which
 means they can't eat as much meat, and poorer appetite. The
 same is the case for vegetarians and vegans."

 She said foods such as textured vegetable proteins, soya,
 pulses and rice and bread were good providers of protein for
 these groups of people.

 A spokeswoman for the Vegan Society said there was not
 usually a problem of low protein intake for vegans, who do
 not eat meat or dairy products.

 "It is just sensible to eat a varied diet," she said. "As
 long as you are doing that, you will be fine."


 Internet links:

    Journal of Clinical Endocrinology and Metabolism
    http://www.scherago.com/endo_journals/jcem.html


~~~~~~~

 http://news.bbc.co.uk/hi/english/health/newsid_286000/286265.stm


 Vegetarian diet linked to genital defects

 A vegetarian diet may put babies at risk

 by BBC Bristol health correspondent Matthew Hill
 BBC News Online - Health
 Thursday, February 25, 1999


 A vegetarian diet could be responsible for genital
 defects in baby boys, according to BBC-funded research
 carried out by scientists in Bristol.

 Researchers found that boys born to vegetarian mums are
 five times more likely to suffer from hypospadias, a
 condition that effects the male urethra.  The urethra is
 the tube that carries the urine from the bladder to an
 external opening.

 In males, the urethra should open at the tip of the
 penis.  If the urethra opens below the tip of the penis,
 this is called hypospadias.

 There are various grades of hypospadias depending on how
 far down the shaft of the penis the urethral opening is
 located.

 The only way to correct this is with surgery, which is
 usually performed at one to two years of age.

 Children with hypospadias should never be circumsized as
 the foreskin may be used to repair the hypospadias.

 Hypospadias is very painful, often combined with
 undescended testicles and could lead to testicular
 cancer.

 The number of cases of hypospadias has doubled in the
 past 30 years.

 The increase mirrors an increase in other problems with
 the male reproductive system such as low sperm count,
 undescended testicles and testicular cancer.

 The research was carried out by Bristol University's
 "Children of the 90s" Project which is investigating the
 health of 14,000 children born at the start of this
 decade.

 The researchers found 51 boys suffering from
 hypospadias.


 Pesticides implicated

 They believe that a vegetarian diet alone is unlikely to
 cause hypospadias.

 But they think vegetarians are probably eating more of
 something that is to blame -- soya is a suspect.

 According to the researchers, the defect may be caused
 by crop pesticides or naturally occurring chemicals
 called phytoestrogens.

 Phytoestrogens are generally thought to be behind
 hormonal imbalances leading to defects.

 The researchers say that more investigations are needed
 before the link can be properly established.

 Project leader Professor Jean Golding says:  "We know
 that vegetables are good for all sorts of reasons and we
 are certainly not advocating that people stop eating
 vegetables.

 "We think, however, that such studies may help us find
 answers to this distressing condition.

 "It is potentially disastrous for the human race, and it
 is important that it is addressed early."

 Professor Golding said the majority of mothers of
 affected boys were meat-eaters, but proportionately
 vegetarian mothers were at greater risk of producing a
 boy with the condition.

 Kym Godier, 32, of Wells, Somerset, began a parents'
 national support group after her son Thomas was born
 with the hypospadias defect.

 Thomas, now three, had corrective surgery and is "fine",
 says his mother.

 She said:  "I was shocked and confused when I heard of
 this condition as there seemed no-one to turn to for
 explanation.

 "I was surprised to hear that vegetarians were more at
 risk as you generally think of them leading a healthier
 lifestyle."





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