Quick update - upstream was very happy to see a first bunch of patches and created https://github.com/GENtle-persons/gentle-m with membership to GENtle-persons initially offered to Andreas and myself (I already accepted).
So, I think my next steps are to transfer d/patches/* to an upstream dev branch and then sync with upstream about a new point release. Best, Steffen > Gesendet: Montag, 31. Juli 2023 um 12:39 Uhr > Von: "Steffen Möller" <steffen_moel...@gmx.de> > An: "Med Team" <debian-med@lists.debian.org> > Betreff: GENtle - some progress > > Hello, > > I just uploaded another iteration of GENtle to our servers. It has some > quirks, still, as in that wxWidgets' runtime checks kick in with the one or > other window that is opened, something about the windows parents not set > right, but I guess this is usable. I'll finish this up over the next weeks. > > Some background, GENtle comes from a time when the cloning of DNA (as in: get > some large string of unknown DNA of interest connected in a much larger piece > of well-known DNA that can be multiplied by bacteria) was a precondition to > get that DNA sequenced. With technological advancements that has mostly been > substituted with "let us just sequence the whole organism". And there is > software like https://www.snapgene.com/ doing many things right that come to > a rescue for smaller groups and/or smaller projects, and for all the many > tasks like amplifying the gene product of what was cloned (as in producing > insulin, see https://openinsulin.org/). > > IMHO times have changed again in that we already have sequenced of what we > want to see sequenced and now the research community shifted from "get DNA > out from human cells" to "get DNA into (typically cultures of) human cells". > To move any gene across the cell wall, you need a special kind of vehicle, > and technically those look just like those plasmids that GENtle already knows > how to design. So this is not just some old outdated technology lurking with > us, we should just think about how we can modernize the GUI a bit and maybe > add some public data. > > I'll discuss data to be added with my wet-lab colleagues, also some > imperfections in software may be ideal as student projects to > describe/fix/learn, will see. > > Best, > Steffen > >
