Yeah.
My first thought on looking at this was that getting the dosing right is going
to be a bear. Now you not only have to deal with variation among people in
mRNA expression levels, but you have to manage variation in the amplifier by an
RDRP (RNA-dependent RNA polymerase).
My thoughts
The space between */Scylla and Charybdis/ *seems to be shrinking by
halves. On the one had the conspiracists are "awfulizing" everything
while others might be "normalizing" everything in the spirit of
(polyanna?) progress?
With what *appears* to be a sharp rise in auto-immune disorders in
https://sciencebasedmedicine.org/self-amplifying-rna-vaccines/?utm_source=rss_medium=rss_campaign=self-amplifying-rna-vaccines
"It is also likely that there will be another round of fear-mongering about the
new technology. It probably best for scientists to get ahead of this, to
introduce and