)^2 ## = 0.51955
err.1-7.04
rse.err.1-54.4#%
var.err.1-(rse.err.1*err.1/100)^2 ## = 14.66
##now from delta method
E(err)=2.65^2 ## 7.025 close to 7.04
var(err)=(2*2.65)^2*0.51955 ## 14.59 close to 14.66
Hope it helps
Varun Goel
PhD Candidate, Pharmacometrics
Experimental
Dear Mohamed,
A logit transformation of data will transform your VAS scores from - infinity
to + infinity.
Varun Goel
--- On Mon, 6/16/08, [EMAIL PROTECTED] lt;[EMAIL PROTECTED]gt; wrote:
From: [EMAIL PROTECTED] lt;[EMAIL PROTECTED]gt;
Subject: [NMusers] Log Transformation in NONMEM
Hi Varun, You might try explicitly using “NOINTERACTION”
with SAEM and IMP. Cheers… Brian From: owner-nmus...@globomaxnm.com
[mailto:owner-nmus...@globomaxnm.com]On Behalf Of varun goel
Sent: Friday, January 13, 2017 9:55 AM
To: nmusers@globomaxnm.com
Subject: [NMusers] Error with SAEM
Dear All, I get error while using SAEM estimation method for repeated time to
event model. But, the same model runs well with LAPLACE. Could you suggest what
I am missing below.
This $EST runs well$ESTIMATION MAXEVAL=999 METHOD=COND LAPLACE LIKE PRINT=1
Following $EST method fails with the
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Alnylam was founded in 2002 on a revolutionary vision and bold mission which
remain firmly in place today. We are leading the translation of RNAi as a new
class of medicines with a core focus on RNAi therapeutics toward genetically
defined targets for the treatment of serious,