Re: [R] using lsoda() and nls() together

bbouling wrote: Thanks to Dieter Menne and Spencer Graves I started to get my way through lsoda() Now I need to use it in with nls() to assess parameters I have a go with a basic example dy/dt = K1*conc I try to assess the value of K1 from a simulated data set with a K1 close to

[R] using lsoda() and nls() together

Thanks to Dieter Menne and Spencer Graves I started to get my way through lsoda() Now I need to use it in with nls() to assess parameters I have a go with a basic example dy/dt = K1*conc I try to assess the value of K1 from a simulated data set with a K1 close to 2. Here is (I think) the best

Re: [R] using lsoda() and nls() together

Hi Benoit, your problem is not really a problem of lsoda. The reason of the crash is a violation of the statistical assumptions of least squares regression due to dependency of residual variance on x. Due to this, K1 is varied over a very large range of values until numeric overflow occurs.