Sorry I'm late with this.
On 07/26/2013 02:02 PM, Terry Therneau wrote:
Two choices. If this were a linear model, do you like the GEE
approach or a mixed effects approach? Assume that subject is a
variable containing a per-subject identifier.
GEE approach: add + cluster(subject) to the model
On 07/26/2013 04:06 AM, John Sorkin wrote:
David Thank you for your thoughts. The data I am analyzing do not
come from a clinical trial but rather from a cohort study whose aim
is to determine risk factors for surgical therapy to treat their
joints. John
As David explained, there are several
Two choices.
If this were a linear model, do you like the GEE approach or a mixed effects approach?
Assume that subject is a variable containing a per-subject identifier.
GEE approach: add + cluster(subject) to the model statement in coxph
Mixed models approach: Add + (1|subject) to the
Thanks Terry.
Good points. I recalled last night some exchanges on r-sig-mixed-models
regarding a reasonable number of 'replications' for the estimation of random
effects and it occurred to me that with this study, you will have 0, 1 or 2
events per subject, depending upon the subject risk
Marc,
Thank you for your comments. The data has been previously collected, so the
study is a non-concurrent prospective analysis, i.e. retrospective analysis.
John
John David Sorkin M.D., Ph.D.
Professor of Medicine
Chief, Biostatistics and Informatics
University of Maryland School of Medicine
Colleagues,
Is there any R package that will allow one to perform a repeated measures Cox
Proportional Hazards regression? I don't think coxph is set up to handle this
type of problem, but I would be happy to know that I am not correct.
I am doing a study of time to hip joint replacement. As
On Jul 25, 2013, at 2:11 PM, John Sorkin jsor...@grecc.umaryland.edu wrote:
Colleagues,
Is there any R package that will allow one to perform a repeated measures Cox
Proportional Hazards regression? I don't think coxph is set up to handle this
type of problem, but I would be happy to know
On Jul 25, 2013, at 12:27 PM, Marc Schwartz wrote:
On Jul 25, 2013, at 2:11 PM, John Sorkin jsor...@grecc.umaryland.edu wrote:
Colleagues,
Is there any R package that will allow one to perform a repeated measures
Cox Proportional Hazards regression? I don't think coxph is set up to
On Jul 25, 2013, at 4:45 PM, David Winsemius dwinsem...@comcast.net wrote:
On Jul 25, 2013, at 12:27 PM, Marc Schwartz wrote:
On Jul 25, 2013, at 2:11 PM, John Sorkin jsor...@grecc.umaryland.edu wrote:
Colleagues,
Is there any R package that will allow one to perform a repeated
David
Thank you for your thoughts.
The data I am analyzing do not come from a clinical trial but rather from a
cohort study whose aim is to determine risk factors for surgical therapy to
treat their joints.
John
Sent from my iPhone
On Jul 25, 2013, at 9:15 PM, Marc Schwartz
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