[R] DNA sequence Fst

2010-08-23 Thread blue jay
Hi, I want to analyse DNA sequence data (mtDNA) in R as in calculate Fst, Heterozygosity and such summary statistics. Package Adagenet converts the DNA sequence into retaining only retaining the polymorphic sites and then calcuates Fst.. but is there any other way to do this? I mean analyse the

Re: [R] DNA sequence Fst

2010-08-23 Thread Tim Gruene
Hello Blue Ray, I have worked with DNA, but frankly I do not know what Fst, Heterozygosity and such summary statistics might be. If you could explain a little, maybe even give a reference about their meaning and how to do the calculations, people who are not biologists but know R might be able

Re: [R] DNA sequence Fst

2010-08-23 Thread Charles Roosen
regards, Charlie Roosen Mango Solutions -Original Message- From: r-help-boun...@r-project.org [mailto:r-help-boun...@r-project.org] On Behalf Of blue jay Sent: 23 August 2010 12:30 To: r-help@r-project.org Subject: [R] DNA sequence Fst Hi, I want to analyse DNA sequence data (mtDNA) in R

Re: [R] DNA sequence Fst

2010-08-23 Thread Keo Ormsby
Hi Blue Jay, If your sequences are small (10Kb) and you have a few samples (~100) the seqinr package from CRAN itself is a very straightforward way of handling DNA sequences, but if you plan to do more sophisticated things that can drain your RAM and processor time, I would definitely