Hi Steve,

You make it seem that Argyria is a disease. 

Do you think that argyria is a disease? To my mind it is merely a 
colouration and is perhaps an indicator of something. But I know of no 
detriment other that the colour. What are the downsides of having 
argyria?

OK,
Tony



On 13 Jul 2009 at 16:25, Norton, Steve wrote about :
Subject : CS>How to tell Stage I argyria from

> 
> OK, so there is no argyria Stage I, II, III or IV  defined, but I would
> like to suggest that defining different stages of argyria would be much
> more useful than the single stage used today. I think that argyria is
> greatly under reported because a person has to turn nearly completely grey
> or blue for it to be reported as argyria. In actuality, once any of the
> visible tissues turns grey/blue that person has argyria and it is just a
> matter of how severe a case it is.
>  I would like to suggest different stages, such as those used for
> cancer, to identify argyria and the extent of the argyria. The stages for
> cancer are (from Wikipedia): *        Stage I cancers are localized to one 
> part
> of the body. *        Stage II cancers are locally advanced. *        Stage 
> III cancers
> are also locally advanced. Whether a cancer is designated as Stage II or
> Stage III can depend on the specific type of cancer; for example, in
> Hodgkin's Disease, Stage II indicates affected lymph nodes on only one
> side of the diaphragm, whereas Stage III indicates affected lymph nodes
> above and below the diaphragm. The specific criteria for Stages II and III
> therefore differ according to diagnosis. *    Stage IV cancers have often
> metastasized, or spread to other organs or throughout the body
> 
> How about something for argyria like:
> *     Stage I - Argyria is localized to light browning of the gums or
> light browning of the skin exposed to sunlight 
> *     Stage II - Argyria is localized to fingernails or a slight
> coloring of the eyes. 
> *     Stage III - Argyria is also localized to the face and neck as a
> blue/grey color or a significant darkening of eyes.
> *     Stage IV - Argyria is generally spread throughout the body or a
> near or total darkening of eyes.
> 
> The stages I suggest may not be the best. From what I have read, it may be
> difficult to determine a Stage I condition. Plus, I tried to cover the
> coloring of the eyes (ocular argyrosis) in the proposed stages. Maybe the
> eyes should be separate. Does anyone else think that this might be better
> than the current single declaration of argyria? Any suggestions for
> improvement?
> 
> Thanks,
>      Steve N
> 
> 



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